We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
A feasibility study on AI-controlled closed-loop electrical stimulation implants.
- Authors
Eickhoff, Steffen; Garcia-Agundez, Augusto; Haidar, Daniela; Zaidat, Bashar; Adjei-Mosi, Michael; Li, Peter; Eickhoff, Carsten
- Abstract
Miniaturized electrical stimulation (ES) implants show great promise in practice, but their real-time control by means of biophysical mechanistic algorithms is not feasible due to computational complexity. Here, we study the feasibility of more computationally efficient machine learning methods to control ES implants. For this, we estimate the normalized twitch force of the stimulated extensor digitorum longus muscle on n = 11 Wistar rats with intra- and cross-subject calibration. After 2000 training stimulations, we reach a mean absolute error of 0.03 in an intra-subject setting and 0.2 in a cross-subject setting with a random forest regressor. To the best of our knowledge, this work is the first experiment showing the feasibility of AI to simulate complex ES mechanistic models. However, the results of cross-subject training motivate more research on error reduction methods for this setting.
- Subjects
ELECTRIC stimulation; FEASIBILITY studies; REAL-time control; RANDOM forest algorithms; LABORATORY rats; ADAPTIVE fuzzy control
- Publication
Scientific Reports, 2023, Vol 13, Issue 1, p1
- ISSN
2045-2322
- Publication type
Article
- DOI
10.1038/s41598-023-36384-x