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- Title
Calcium and Phosphorus Deficiencies in Patients with Liver Cirrhosis.
- Authors
IONELE, CLAUDIU MARINEL; SUBTIRELU, MIHAELA SIMONA; UNGUREANU, BOGDAN SILVIU; SERBANESCU, MIRCEA-SEBASTIAN; ROGOVEANU, ION
- Abstract
Patients with cirrhosis often develop malnutrition and micronutrient deficiencies, leading to a worse prognosis and increased mortality. Our purpose was to assess the prevalence of micronutrient deficiencies especially calcium and phosphorus in patients with decompensated liver cirrhosis (LC). This was a retrospective study including 143 consecutive patients hospitalized for acute decompensation of cirrhosis, most of them with alcoholic etiology along with viral B or viral C and autoimmune induced cirrhosis. A blood test including minerals was performed on admission. Lower serum calcium levels were found in patients with a more severe forms of LC and also the ones diagnosed with viral and alcoholic LC rather than autoimmune induced LC. Peritoneal ascitic fluid was observed in 51 patients with hypocalcemia and only 24 patients with normal calcium levels had fluid accumulation. Low levels of phosphorus were noted in patients with a more severe form of LC (chi-square: 20.2504; p-value 0.000446). Ascitic fluid was found in patients with low values of phosphorus as well as in those with hypocalcemia (chi-square 5.235; p-value 0.022137). In conclusion, this study confirmed that patients with advanced liver disease had lower values of calcium and phosphorus and a more severe form of LC can be associated with hypocalcemia and hypophosphatemia.
- Subjects
CIRRHOSIS of the liver; HYPOPHOSPHATEMIA; DEFICIENCY diseases; CALCIUM; ASCITIC fluids; PHOSPHORUS
- Publication
Current Health Sciences Journal, 2022, Vol 48, Issue 3, p311
- ISSN
2067-0656
- Publication type
Article
- DOI
10.12865/CHSJ.48.03.09