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- Title
Generalized Periodic Epileptiform Discharges in a Child With Dravet Syndrome.
- Authors
Moseley, Brian D.; Wirrell, Elaine C.; Nickels, Katherine
- Abstract
Generalized periodic epileptiform discharges can occur in a variety of epileptic syndromes and herald impending seizures. Such discharges are also extremely rare in children. Cerebral visual impairment can be associated with generalized and partial onset seizures, particularly those involving the occipital lobe. The authors present a case of a 10-month-old boy whose electroencephalogram revealed generalized periodic epileptiform discharges following resolution of status epilepticus. Such discharges warranted further monitoring, during which he experienced 2 additional seizures. He also was discovered to have cerebral visual impairment, which slowly resolved following termination of seizure activity. The child was subsequently found to have a de novo mutation of the sodium channel, voltage-gated, type I, alpha subunit (SCN1A) gene consistent with Dravet syndrome.
- Subjects
CHILDREN with epilepsy; VISION disorders in children; SEIZURES (Medicine); OCCIPITAL lobe; SODIUM channels; ELECTROENCEPHALOGRAPHY
- Publication
Journal of Child Neurology, 2011, Vol 26, Issue 7, p907
- ISSN
0883-0738
- Publication type
Case Study
- DOI
10.1177/0883073810394182