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- Title
Electrochemical Sulphenylation/Cyclization of Quinones: A Rapid, Green, and Efficient Access to Cytotoxic Compounds.
- Authors
Diogo, Emilay B. T.; Delolo, Fábio G.; Graça, Gabriela A. P.; Paz, Esther R. S.; Bozzi, Ícaro A. O.; Diniz, Renata; Passos, Juliano P.; Matencio, Tulio; Soares, Liane K.; Alves, Diego; Costa, Pedro M. S.; Pessoa, Claudia; Pereira, Cynthia L. M.; Ackermann, Lutz; da Silva Júnior, Eufrânio N.
- Abstract
Undivided electrochemical cells enable economical preparation of sulphur‐containing naphthoquinones through electrochemical sulphenylation of quinoidal compounds. The environmentally friendly and efficient protocol eliminates the use of chemical oxidants and facilitates the synthesis of the desired molecules. This approach offers an efficient and versatile method to synthesize quinones that exhibit cytotoxicity against cancer cell lines.
- Subjects
RING formation (Chemistry); ELECTRIC batteries; CYTOTOXINS; CELL lines; QUINONE; CANCER cells
- Publication
European Journal of Organic Chemistry, 2023, Vol 26, Issue 38, p1
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.202300506