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- Title
Permanent Pacing for Late-Onset Atrioventricular Block in Patients with Heart Transplantation: A Single Center Experience.
- Authors
TAY, ANDRE E.; FADDY, STEVEN; LIM, SERN; WALKER, BRUCE D.; KUCHAR, DENNIS; THORBURN, CHARLES W.; MACDONALD, PETER; KEOGH, ANNE; KOTLYAR, EUGENE; FARNSWORTH, ALAN; HAYWARD, CHRIS; JANSZ, PAUL; GRANGER, EMILY; SPRATT, PHILLIP; SUBBIAH, RAJESH N.
- Abstract
The incidence, mechanisms, clinical associations, and outcomes in patients with late-onset (>3 months) atrioventricular (AV) block following heart transplantation are not well known. This study will characterize late-onset AV block following cardiac transplantation. We retrospectively reviewed our databases to identify patients who required pacemakers for late-onset AV block postheart and heart-lung transplantation from January 1990 to December 2007. Orthotopic heart and heart-lung transplantation were separately analyzed. This study included 588 adults who received cardiac transplants over a 17-year period at our center (519 orthotopic, 64 heart-lung transplants, and five heterotopic heart transplants). Of the 519 patients with orthotopic heart transplant, 39 required pacing (7.5%), 17 (3.3%) within 3 months posttransplant, 11 (2.1%) for late-onset sinus node dysfunction (SND), 11 (2.1%) for late-onset AV block. Also, five patients (7.8%) out of 64 heart-lung transplants required pacemakers, two (3.1%) for late-onset SND, three (4.7%) for late-onset AV block. None of the five patients who underwent heterotopic transplant required cardiac pacing prior to or posttransplant. Late-onset AV block occurs in 2.4% of patients with orthotopic heart transplant or heart-lung transplant. AV block is predominantly intermittent and, often, does not progress to permanent AV block. There are no predictable factors for its onset. (PACE 2011; 72-75)
- Subjects
AUSTRALIA; CARDIAC pacemakers; HEART transplantation; HEART block; LUNG transplantation; HEALTH outcome assessment; TREATMENT effectiveness; RETROSPECTIVE studies
- Publication
Pacing & Clinical Electrophysiology, 2011, Vol 34, Issue 1, p72
- ISSN
0147-8389
- Publication type
Article
- DOI
10.1111/j.1540-8159.2010.02906.x