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JS-K has potent anti-angiogenic activity in vitro and inhibits tumour angiogenesis in a multiple myeloma model in vivo.
Published in:
Journal of Pharmacy & Pharmacology, 2010, v. 62, n. 1, p. 145, doi. 10.1211/jpp.62.01.0017
By:
- Kiziltepe, Tanyel;
- Anderson, Kenneth C.;
- Kutok, Jeffery L.;
- Jia, Lee;
- Boucher, Kenneth M.;
- Saavedra, Joseph E.;
- Keefer, Larry K.;
- Shami, Paul J.
Publication type:
Article
Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning.
Published in:
Nature Medicine, 2002, v. 8, n. 1, p. 68, doi. 10.1038/nm0102-68
By:
- Shipp, Margaret A.;
- Ross, Ken N.;
- Tamayo, Pablo;
- Weng, Andrew P.;
- Kutok, Jeffery L.;
- Aguiar, Ricardo C.T.;
- Gaasenbeek, Michelle;
- Angelo, Michael;
- Reich, Michael;
- Pinkus, Geraldine S.;
- Ray, Tane S.;
- Koval, Margaret A.;
- Last, Kim W.;
- Norton, Andrew;
- Lister, T. Andrew;
- Mesirov, Jill;
- Neuberg, Donna S.;
- Lander, Eric S.;
- Aster, Jon C.
Publication type:
Article
Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.
Published in:
EMBO Journal, 2005, v. 24, n. 2, p. 368, doi. 10.1038/sj.emboj.7600521
By:
- Wang, Jing;
- Iwasaki, Hiromi;
- Krivtsov, Andrei;
- Febbo, Phillip G.;
- Thorner, Aaron R.;
- Ernst, Patricia;
- Anastasiadou, Ema;
- Kutok, Jeffery L.;
- Kogan, Scott C.;
- Zinkel, Sandra S.;
- Fisher, Jill K.;
- Hess, Jay L.;
- Golub, Todd R.;
- Armstrong, Scott A.;
- Akashi, Koichi;
- Korsmeyer, Stanley J.
Publication type:
Article
Fine-needle aspiration cytology of lymphoproliferative disorders in the immunosuppressed patient: The diagnostic utility of in situ hybridization for Epstein-Barr virus.
Published in:
Diagnostic Cytopathology, 2002, v. 26, n. 6, p. 360, doi. 10.1002/dc.10113
By:
- Hecht, Jonathan L.;
- Cibas, Edmund S.;
- Kutok, Jeffery L.
Publication type:
Article
Hematopoietic Stem Cell Defects in Mice with Deficiency of Fancd2 or Usp1.
Published in:
Stem Cells, 2010, v. 28, n. 7, p. 1186, doi. 10.1002/stem.437
By:
- Parmar, Kalindi;
- Kim, Jungmin;
- Sykes, Stephen M.;
- Shimamura, Akiko;
- Stuckert, Patricia;
- Zhu, Kaya;
- Hamilton, Abigail;
- Deloach, Mary Kathryn;
- Kutok, Jeffery L.;
- Akashi, Koichi;
- Gilliland, D. Gary;
- D'andrea, Alan
Publication type:
Article
Autocrine activation of the MET receptor tyrosine kinase in acute myeloid leukemia.
Published in:
Nature Medicine, 2012, v. 18, n. 7, p. 1118, doi. 10.1038/nm.2819
By:
- Kentsis, Alex;
- Reed, Casie;
- Rice, Kim L;
- Sanda, Takaomi;
- Rodig, Scott J;
- Tholouli, Eleni;
- Christie, Amanda;
- Valk, Peter J M;
- Delwel, Ruud;
- Ngo, Vu;
- Kutok, Jeffery L;
- Dahlberg, Suzanne E;
- Moreau, Lisa A;
- Byers, Richard J;
- Christensen, James G;
- Woude, George Vande;
- Licht, Jonathan D;
- Kung, Andrew L;
- Staudt, Louis M;
- Look, A Thomas
Publication type:
Article
Mouse model of Noonan syndrome reveals cell type- and gene dosage-dependent effects of Ptpn11 mutation.
Published in:
Nature Medicine, 2004, v. 10, n. 8, p. 849, doi. 10.1038/nm1084
By:
- Araki, Toshiyuki;
- Mohi, M. Golam;
- Ismat, Fraz A.;
- Bronson, Roderick T.;
- Williams, Ifor R.;
- Kutok, Jeffery L.;
- Wentian Yang;
- Pao, Lily I.;
- Gilliland, D. Gary;
- Epstein, Jonathan A.;
- Neep, Benjamin G.
Publication type:
Article
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1.
Published in:
Nature Genetics, 2006, v. 38, n. 1, p. 27, doi. 10.1038/ng1679
By:
- Rosenbauer, Frank;
- Owens, Bronwyn M.;
- Li Yu;
- Tumang, Joseph R.;
- Steidl, Ulrich;
- Kutok, Jeffery L.;
- Clayton, Linda K.;
- Wagner, Katharina;
- Scheller, Marina;
- Iwasaki, Hiromi;
- Liu, Chunhui;
- Hackanson, Björn;
- Akashi, Koichi;
- Leutz, Achim;
- Rothstein, Thomas L.;
- Plass, Christoph;
- Tenen, Daniel G.
Publication type:
Article
Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.
Published in:
Nature Genetics, 2004, v. 36, n. 6, p. 624, doi. 10.1038/ng1361
By:
- Rosenbauer, Frank;
- Wagner, Katharina;
- Kutok, Jeffery L.;
- Iwasaki, Hiromi;
- Le Beau, Michelle M.;
- Okuno, Yutaka;
- Akashi, Koichi;
- Fiering, Steven;
- Tenen, Daniel G.
Publication type:
Article
HSP90 Inhibition Enhances Antimitotic Drug-Induced Mitotic Arrest and Cell Death in Preclinical Models of Non-Small Cell Lung Cancer.
Published in:
PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0115228
By:
- O'Connell, Brenda C.;
- O'Callaghan, Katie;
- Tillotson, Bonnie;
- Douglas, Mark;
- Hafeez, Nafeeza;
- West, Kip A.;
- Stern, Howard;
- Ali, Janid A.;
- Changelian, Paul;
- Fritz, Christian C.;
- Palombella, Vito J.;
- McGovern, Karen;
- Kutok, Jeffery L.
Publication type:
Article
Impact of the Smoothened Inhibitor, IPI-926, on Smoothened Ciliary Localization and Hedgehog Pathway Activity.
Published in:
PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0090534
By:
- Peluso, Marisa O.;
- Campbell, Veronica T.;
- Harari, Joseph A.;
- Tibbitts, Thomas T.;
- Proctor, Jennifer L.;
- Whitebread, Nigel;
- Conley, James M.;
- White, Kerry F.;
- Kutok, Jeffery L.;
- Read, Margaret A.;
- McGovern, Karen;
- Faia, Kerrie L.
Publication type:
Article
FGFR3 as a therapeutic target of the small molecule inhibitor PKC412 in hematopoietic malignancies.
Published in:
Oncogene, 2005, v. 24, n. 56, p. 8259, doi. 10.1038/sj.onc.1208989
By:
- Jing Chen;
- Lee, Benjamin H.;
- Williams, Ifor R.;
- Kutok, Jeffery L.;
- Mitsiades, Constantine S.;
- Duclos, Nicole;
- Cohen, Sarah;
- Adelsperger, Jennifer;
- Okabe, Rachel;
- Coburn, Allison;
- Moore, Sandra;
- Huntly, Brian J. P.;
- Fabbro, Doriano;
- Anderson, Kenneth C.;
- Griffin, James D.;
- Gilliland, Dwight Gary
Publication type:
Article
B-acute lymphoblastic leukemia/lymphoblastic lymphoma.
Published in:
2015
By:
- Loghavi, Sanam;
- Kutok, Jeffery L;
- Jorgensen, Jeffrey L
Publication type:
journal article
B-Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma.
Published in:
American Journal of Clinical Pathology, 2015, v. 144, n. 3, p. 393, doi. 10.1309/AJCPAN7BH5DNYWZB
By:
- Loghavi, Sanam;
- Kutok, Jeffery L.;
- Jorgensen, Jeffrey L.
Publication type:
Article
CD52 Is Expressed on Human Mast Cells and Is a Potential Therapeutic Target in Waldenström's Macroglobulinemia and Mast Cell Disorders.
Published in:
Clinical Lymphoma & Myeloma, 2006, v. 6, n. 6, p. 478
By:
- Ditzel Santos, Daniel;
- Hatjiharissi, Evdoxia;
- Tournilhac, Olivier;
- Chemaly, Mariana Z.A.;
- Leleu, Xavier;
- Xu, Lian;
- Patterson, Christopher;
- Branagan, Andrew R.;
- Manning, Robert J.;
- Ho, Allen W.;
- Hunter, Zachary R.;
- Dimmock, Elizabeth A.;
- Kutok, Jeffery L.;
- Churchill, Winthrop H.;
- Castells, Mariana C.;
- Tai, Yu-Tzu;
- Anderson, Kenneth C.;
- Treon, Steven P.
Publication type:
Article
Strategies for H-score normalization of preanalytical technical variables with potential utility to immunohistochemical-based biomarker quantitation in therapeutic reponse diagnostics.
Published in:
Analytical Cellular Pathology: Cellular Oncology, 2011, v. 34, n. 3, p. 159, doi. 10.1155/2011/583182
By:
- Pierceall, William E.;
- Wolfe, Michele;
- Suschak, Jessica;
- Chang, Hua;
- Chen, Yan;
- Sprott, Kam M.;
- Kutok, Jeffery L.;
- Quan, Stella;
- Weaver, David T.;
- Ward, Brian E.
Publication type:
Article
Characterization of the expression of HTm4 (MS4A3), a cell cycle regulator, in human peripheral blood cells and normal and malignant tissues.
Published in:
Journal of Cellular & Molecular Medicine, 2011, v. 15, n. 1, p. 86, doi. 10.1111/j.1582-4934.2009.00925.x
By:
- Kutok, Jeffery L.;
- Yang, Xing;
- Folkerth, Rebecca;
- Adra, Chaker N.
Publication type:
Article
53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.
Published in:
Nature Immunology, 2004, v. 5, n. 5, p. 481, doi. 10.1038/ni1067
By:
- Manis, John P.;
- Morales, Julio C.;
- Xia, Zhenfang;
- Kutok, Jeffery L.;
- Alt, Frederick W.;
- Carpenter, Philip B.
Publication type:
Article
B cell receptor signal strength determines B cell fate.
Published in:
Nature Immunology, 2004, v. 5, n. 3, p. 317, doi. 10.1038/ni1036
By:
- Casola, Stefano;
- Otipoby, Kevin .;
- Alimzhanov, Marat;
- Humme, Sibille;
- Uyttersprot, Nathalie;
- Kutok, Jeffery L.;
- Carroll, Michael C.;
- Rajewsky, Klaus
Publication type:
Article
The Selective Phosphoinoside- 3-Kinase p110δ Inhibitor IPI-3063 Potently Suppresses B Cell Survival, Proliferation, and Differentiation.
Published in:
Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.00747
By:
- Chiu, Honyin;
- Mallya, Sharmila;
- Nguyen, Phuongthao;
- Mai, Annie;
- Jackson, Leandra V.;
- Winkler, David G.;
- DiNitto, Jonathan P.;
- Brophy, Erin E.;
- McGovern, Karen;
- Kutok, Jeffery L.;
- Fruman, David A.
Publication type:
Article
Aggressive Langerhans cell histiocytosis following T-ALL: Clonally related neoplasms with persistent expression of constitutively active NOTCH1.
Published in:
American Journal of Hematology, 2008, v. 83, n. 2, p. 116, doi. 10.1002/ajh.21044
By:
- Rodig, Scott J.;
- Payne, Ethan G.;
- Degar, Barbara A.;
- Rollins, Barrett;
- Feldman, Andrew L.;
- Jaffe, Elaine S.;
- Androkites, Arlene;
- Silverman, Lewis B.;
- Longtine, Janina A.;
- Kutok, Jeffery L.;
- Fleming, Mark D.;
- Aster, Jon C.
Publication type:
Article
Matrix metalloproteinases in the urine and tissue of patients with juvenile polyps: potential biomarkers for the presence of polyps.
Published in:
2009
By:
- Manfredi MA;
- Fox VL;
- Zurakowski D;
- Kutok JL;
- Glickman JN;
- Moses MA;
- Manfredi, Michael A;
- Fox, Victor L;
- Zurakowski, David;
- Kutok, Jeffery L;
- Glickman, Jonathan N;
- Moses, Marsha A
Publication type:
journal article
Impact of hemochromatosis gene mutations on cardiac status in doxorubicin-treated survivors of childhood high-risk leukemia.
Published in:
Cancer (0008543X), 2013, v. 119, n. 19, p. 3555, doi. 10.1002/cncr.28256
By:
- Lipshultz, Steven E.;
- Lipsitz, Stuart R.;
- Kutok, Jeffery L.;
- Miller, Tracie L.;
- Colan, Steven D.;
- Neuberg, Donna S.;
- Stevenson, Kristen E.;
- Fleming, Mark D.;
- Sallan, Stephen E.;
- Franco, Vivian I.;
- Henkel, Jacqueline M.;
- Asselin, Barbara L.;
- Athale, Uma H.;
- Clavell, Luis A.;
- Michon, Bruno;
- Laverdiere, Caroline;
- Larsen, Eric;
- Kelly, Kara M.;
- Silverman, Lewis B.
Publication type:
Article
Phase II study of a TLR-9 agonist (1018 ISS) with rituximab in patients with relapsed or refractory follicular lymphoma.
Published in:
British Journal of Haematology, 2009, v. 146, n. 3, p. 282, doi. 10.1111/j.1365-2141.2009.07773.x
By:
- Friedberg, Jonathan W.;
- Kelly, Jennifer L.;
- Neuberg, Donna;
- Peterson, Derick R.;
- Kutok, Jeffery L.;
- Salloum, Rabih;
- Brenn, Thomas;
- Fisher, David C.;
- Ronan, Elizabeth;
- Dalton, Virginia;
- Rich, Lynn;
- Marquis, Diana;
- Sims, Paul;
- Rothberg, Paul G.;
- Liesveld, Jane;
- Fisher, Richard I.;
- Coffman, Robert;
- Mosmann, Tim;
- Freedman, Arnold S.
Publication type:
Article
The heat shock protein 90 inhibitor IPI-504 induces apoptosis of AKT-dependent diffuse large B-cell lymphomas.
Published in:
British Journal of Haematology, 2009, v. 144, n. 3, p. 358, doi. 10.1111/j.1365-2141.2008.07484.x
By:
- Abramson, Jeremy S.;
- Chen, Wen;
- Juszczynski, Przemyslaw;
- Takahashi, Hidenobu;
- Neuberg, Donna;
- Kutok, Jeffery L.;
- Takeyama, Kunihiko;
- Shipp, Margaret A.
Publication type:
Article
The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron–sulfur cluster biogenesis.
Published in:
Human Molecular Genetics, 2006, v. 15, n. 6, p. 953
By:
- Pondarré, Corinne;
- Antiochos, Brendan B.;
- Campagna, Dean R.;
- Clarke, Stephen L.;
- Greer, Eric L.;
- Deck, Kathryn M.;
- McDonald, Alice;
- Han, An-Ping;
- Medlock, Amy;
- Kutok, Jeffery L.;
- Anderson, Sheila A.;
- Eisenstein, Richard S.;
- Fleming, Mark D.
Publication type:
Article
Emerging Targeted Therapies for Lymphoid Malignancies.
Published in:
Archives of Pathology & Laboratory Medicine, 2012, v. 136, n. 5, p. 476, doi. 10.5858/arpa.2010-0391-RA
By:
- Pozdnyakova, Olga;
- Kutok, Jeffery L.;
- Rodig, Scott J.
Publication type:
Article
Langerhans Cell Histiocytosis Involving the Thymus.
Published in:
2003
By:
- Lee, Benjamin H.;
- George, Suzanne;
- Kutok, Jeffery L.
Publication type:
Abstract

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