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- Title
The development and clinical features of splenic aneurysm associated with liver cirrhosis.
- Authors
Sunagozaka, Hajime; Tsuji, Hirokazu; Mizukoshi, Eishiro; Arai, Kuniaki; Kagaya, Takashi; Yamashita, Tatsuya; Sakai, Akito; Nakamoto, Yasunari; Honda, Masao; Kaneko, Shuichi
- Abstract
Splenic artery aneurysm (SAA) is usually asymptomatic, but can be fatal if it ruptures. Portal hypertensive patients with varix or splenomegaly are sometimes complicated by SAA. However, there have been no large-scale clinical studies regarding whether liver cirrhosis itself is associated with splenic aneurysm regardless of varix or splenomegaly. Methods: In the present study, we retrospectively analyzed 303 cirrhotic patients examined with arteriography. The diagnosis and characteristics of SAAs were determined, and the relation with splenic artery diameter was evaluated. Results: Nine patients (2.97%) had 12 complicated SAAs. The aneurysms, which measured 4–22 mm in diameter, were all saccular, and occurred commonly in the splenic hilum (50.0%). A correlation was noted between splenic artery diameter and aneurysm diameter ( R2=0.706). Aneurysm growth was strongly associated with an increase in diameter of the splenic artery trunk ( R2=0.705), which is closely related to arterial flow. Conclusions: SAA is considered a complication of cirrhosis. The increase in splenic artery diameter may result in SAA enlargement and rupture. Elective procedures should be considered based on the follow-up of main trunk or diameter of the splenic artery in addition to SAA size, a known risk factor of aneurysmal rupture.
- Subjects
ANEURYSMS; VASCULAR diseases; VARICOSE veins; CIRRHOSIS of the liver; ARTERIOGRAPHY; ANGIOGRAPHY
- Publication
Liver International, 2006, Vol 26, Issue 3, p291
- ISSN
1478-3223
- Publication type
Article
- DOI
10.1111/j.1478-3231.2005.01231.x