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Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice.
Published in:
2010
By:
- Del Re, Dominic P.;
- Matsuda, Takahisa;
- Peiyong Zhai;
- Shumin Gao;
- Clark, Geoffrey J.;
- Van Der Weyden, Louise;
- Sadoshima, Junichi;
- Zhai, Peiyong;
- Gao, Shumin
Publication type:
journal article
YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases.
Published in:
2021
By:
- Shohei Ikeda;
- Jihoon Nah;
- Akihiro Shirakabe;
- Peiyong Zhai;
- Shin-ichi Oka;
- Sciarretta, Sebastiano;
- Kun-Liang Guan;
- Hiroaki Shimokawa;
- Junichi Sadoshima;
- Ikeda, Shohei;
- Nah, Jihoon;
- Shirakabe, Akihiro;
- Zhai, Peiyong;
- Oka, Shin-Ichi;
- Guan, Kun-Liang;
- Shimokawa, Hiroaki;
- Sadoshima, Junichi
Publication type:
journal article
Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury.
Published in:
2020
By:
- Nah, Jihoon;
- Peiyong Zhai;
- Chun-Yang Huang;
- Fernández, Álvaro F.;
- Mareedu, Satvik;
- Levine, Beth;
- Junichi Sadoshima;
- Zhai, Peiyong;
- Huang, Chun-Yang;
- Sadoshima, Junichi
Publication type:
journal article
Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling.
Published in:
2016
By:
- Shouji Matsushima;
- Junya Kuroda;
- Peiyong Zhai;
- Tong Liu;
- Shohei Ikeda;
- Narayani Nagarajan;
- Shin-ichi Oka;
- Takashi Yokota;
- Shintaro Kinugawa;
- Chiao-Po Hsu;
- Hong Li;
- Hiroyuki Tsutsui;
- Junichi Sadoshima;
- Matsushima, Shouji;
- Kuroda, Junya;
- Zhai, Peiyong;
- Liu, Tong;
- Ikeda, Shohei;
- Nagarajan, Narayani;
- Oka, Shin-Ichi
Publication type:
journal article
Lats2 promotes heart failure by stimulating p53-mediated apoptosis during pressure overload.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02846-3
By:
- Shao, Dan;
- Zhai, Peiyong;
- Hu, Chengchen;
- Mukai, Risa;
- Sciarretta, Sebastiano;
- Del Re, Dominic;
- Sadoshima, Junichi
Publication type:
Article
Cardiac-specific overexpression of AT1 receptor mutant lacking G alpha q/G alpha i coupling causes hypertrophy and bradycardia in transgenic mice.
Published in:
2005
By:
- Zhai, Peiyong;
- Yamamoto, Mitsutaka;
- Galeotti, Jonathan;
- Liu, Jing;
- Masurekar, Malthi;
- Thaisz, Jill;
- Irie, Keiichi;
- Holle, Eric;
- Yu, Xianzhong;
- Kupershmidt, Sabina;
- Roden, Dan M;
- Wagner, Thomas;
- Yatani, Atsuko;
- Vatner, Dorothy E;
- Vatner, Stephen F;
- Sadoshima, Junichi
Publication type:
journal article
Cardiac-specific overexpression of AT1 receptor mutant lacking Gq/Gi coupling causes hypertrophy and bradycardia in transgenic mice.
Published in:
Journal of Clinical Investigation, 2005, v. 115, n. 11, p. 3045, doi. 10.1172/JCI25330
By:
- Peiyong Zhai;
- Yamamoto, Mitsutaka;
- Galeotti, Jonathan;
- Jing Liu;
- Masurekar, Malthi;
- Thaisz, Jill;
- Irie, Keiichi;
- Holle, Eric;
- Xianzhong Yu;
- Kupershmidt, Sabina;
- Roden, Dan M.;
- Wagner, Thomas;
- Yatani, Atsuko;
- Vatner, Dorothy E.;
- Vatner, Stephen F.;
- Sadoshima, Junichi
Publication type:
Article
Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2.
Published in:
Nature Medicine, 2013, v. 19, n. 11, p. 1478, doi. 10.1038/nm.3322
By:
- Maejima, Yasuhiro;
- Kyoi, Shiori;
- Zhai, Peiyong;
- Liu, Tong;
- Li, Hong;
- Ivessa, Andreas;
- Sciarretta, Sebastiano;
- Del Re, Dominic P;
- Zablocki, Daniela K;
- Hsu, Chiao-Po;
- Lim, Dae-Sik;
- Isobe, Mitsuaki;
- Sadoshima, Junichi
Publication type:
Article
Ser14 phosphorylation of Bcl-xL mediates compensatory cardiac hypertrophy in male mice.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-41595-x
By:
- Nakamura, Michinari;
- Keller, Mariko Aoyagi;
- Fefelova, Nadezhda;
- Zhai, Peiyong;
- Liu, Tong;
- Tian, Yimin;
- Ikeda, Shohei;
- Del Re, Dominic P.;
- Li, Hong;
- Xie, Lai-Hua;
- Sadoshima, Junichi
Publication type:
Article
Nicotinamide Mononucleotide, an Intermediate of NAD<sup>+</sup> Synthesis, Protects the Heart from Ischemia and Reperfusion.
Published in:
PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0098972
By:
- Yamamoto, Takanobu;
- Byun, Jaemin;
- Zhai, Peiyong;
- Ikeda, Yoshiyuki;
- Oka, Shinichi;
- Sadoshima, Junichi
Publication type:
Article
Comparative Analysis of mRNA Isoform Expression in Cardiac Hypertrophy and Development Reveals Multiple Post-Transcriptional Regulatory Modules.
Published in:
PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0022391
By:
- Park, Ji Yeon;
- Li, Wencheng;
- Zheng, Dinghai;
- Zhai, Peiyong;
- Yun Zhao;
- Matsuda, Takahisa;
- Vatner, Stephen F.;
- Sadoshima, Junichi;
- Tian, Bin
Publication type:
Article
Ulk1-dependent alternative mitophagy plays a protective role during pressure overload in the heart.
Published in:
Cardiovascular Research, 2022, v. 118, n. 12, p. 2638, doi. 10.1093/cvr/cvac003
By:
- Nah, Jihoon;
- Shirakabe, Akihiro;
- Mukai, Risa;
- Zhai, Peiyong;
- Sung, Eun Ah;
- Ivessa, Andreas;
- Mizushima, Wataru;
- Nakada, Yasuki;
- Saito, Toshiro;
- Hu, Chengchen;
- Jung, Yong Keun;
- Sadoshima, Junichi
Publication type:
Article
Dietary carbohydrates restriction inhibits the development of cardiac hypertrophy and heart failure.
Published in:
Cardiovascular Research, 2021, v. 117, n. 11, p. 2365, doi. 10.1093/cvr/cvaa298
By:
- Nakamura, Michinari;
- Odanovic, Natalija;
- Nakada, Yasuki;
- Dohi, Satomi;
- Zhai, Peiyong;
- Ivessa, Andreas;
- Yang, Zhi;
- Abdellatif, Maha;
- Sadoshima, Junichi
Publication type:
Article
Thioredoxin-1 maintains mitochondrial function via mechanistic target of rapamycin signalling in the heart.
Published in:
Cardiovascular Research, 2020, v. 116, n. 10, p. 1742, doi. 10.1093/cvr/cvz251
By:
- Oka, Shin-Ichi;
- Chin, Adave;
- Park, Ji Yeon;
- Ikeda, Shohei;
- Mizushima, Wataru;
- Ralda, Guersom;
- Zhai, Peiyong;
- Tong, Mingming;
- Byun, Jaemin;
- Tang, Fan;
- Einaga, Yudai;
- Huang, Chun-Yang;
- Kashihara, Toshihide;
- Zhao, Mengyuan;
- Nah, Jihoon;
- Tian, Bin;
- Hirabayashi, Yoko;
- Yodoi, Junji;
- Sadoshima, Junichi
Publication type:
Article
Myeloid YAP Inhibition Improves Cardiac Phenotype During Pressure Overload Stress.
Published in:
FASEB Journal, 2022, v. 36, p. N.PAG, doi. 10.1096/fasebj.2022.36.S1.R3506
By:
- Francisco, Jamie;
- Zhang, Yu;
- Nakada, Yasuki;
- Hu, Che‐Ming;
- Zhai, Peiyong;
- Del Re, Dominic P.
Publication type:
Article
An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia.
Published in:
2019
By:
- Toshiro Saito;
- Jihoon Nah;
- Shin-ichi Oka;
- Risa Mukai;
- Yoshiya Monden;
- Yasuhiro Maejima;
- Yoshiyuki Ikeda;
- Sebastiano Sciarretta;
- Tong Liu;
- Hong Li;
- Baljinnyam, Erdene;
- Fraidenraich, Diego;
- Fritzky, Luke;
- Peiyong Zhai;
- Shizuko Ichinose;
- Mitsuaki Isobe;
- Chiao-Po Hsu;
- Mondira Kundu;
- Junichi Sadoshima;
- Saito, Toshiro
Publication type:
journal article
Sirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins.
Published in:
Nature Communications, 2017, v. 8, n. 5, p. 15560, doi. 10.1038/ncomms15560
By:
- Kang, Hyeog;
- Oka, Shinichi;
- Lee, Duck-Yeon;
- Park, Junhong;
- Aponte, Angel M.;
- Jung, Young-Sang;
- Bitterman, Jacob;
- Zhai, Peiyong;
- He, Yi;
- Kooshapur, Hamed;
- Ghirlando, Rodolfo;
- Tjandra, Nico;
- Lee, Sean B.;
- Kim, Myung K.;
- Sadoshima, Junichi;
- Chung, Jay H.
Publication type:
Article
A functional interaction between Hippo-YAP signalling and FoxO1 mediates the oxidative stress response.
Published in:
Nature Communications, 2014, v. 5, n. 2, p. 3315, doi. 10.1038/ncomms4315
By:
- Shao, Dan;
- Zhai, Peiyong;
- Del Re, Dominic P.;
- Sciarretta, Sebastiano;
- Yabuta, Norikazu;
- Nojima, Hiroshi;
- Lim, Dae-Sik;
- Pan, Duojia;
- Sadoshima, Junichi
Publication type:
Article
Tfeb-Mediated Transcriptional Regulation of Autophagy Induces Autosis during Ischemia/Reperfusion in the Heart.
Published in:
Cells (2073-4409), 2022, v. 11, n. 2, p. 258, doi. 10.3390/cells11020258
By:
- Nah, Jihoon;
- Sung, Eun-Ah;
- Zhai, Peiyong;
- Zablocki, Daniela;
- Sadoshima, Junichi
Publication type:
Article
Unconventional Signalling Mechanisms Mediated by the Angiotensin II Type 1 Receptor in Cardiovascular Cell Types.
Published in:
High Blood Pressure & Cardiovascular Prevention, 2006, v. 13, n. 4, p. 143, doi. 10.2165/00151642-200613040-00001
By:
- Peiyong Zhai;
- Galeotti, Jonathan;
- Sadoshima, Junichi
Publication type:
Article

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