We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Tranexamic Acid (TXA) for the Hemostatic Treatment of Post-Partum Hemorrhage (PPH): What Key Points Have We Learnt After All These Years?
- Authors
Peitsidis, Panagiotis; Iavazzo, Christos; Gkegkes, Ioannis D.; Laganà, Antonio Simone; Makridima, Sophia; Tsikouras, Panagiotis
- Abstract
Tranexamic acid (TXA), also named Cyclokapron, was initially used in gynecology in several European countries, starting in 1968, as a hemostatic drug in excessive menstrual bleeding and menstrual bleeding associated with intrauterine devices (IUDs) [[6], [8]]. Post-partum bleeding or post-partum hemorrhage (PPH) is often defined as the loss of more than 500 mL of blood after vaginal delivery or 1000 mL of blood after cesarean section following the delivery of a child [[1]]. In 2018, Ageron et al. [[18]] performed a metanalysis based on 40,138 patients from two randomized trials of tranexamic acid for acute severe bleeding (traumatic and post-partum hemorrhage - WOMAN and CRASH-2 trial) [[19]].
- Subjects
TRANEXAMIC acid; POSTPARTUM hemorrhage; DELIVERY (Obstetrics); BLOOD loss estimation; SMOOTH muscle contraction; SURGICAL blood loss
- Publication
Journal of Clinical Medicine, 2023, Vol 12, Issue 19, p6385
- ISSN
2077-0383
- Publication type
Article
- DOI
10.3390/jcm12196385