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- Title
Nonadherence as 4-day Antiretroviral Therapy Interruptions: Do Depression and Race/Ethnicity Matter as Much in the Modern Antiretroviral Therapy Era?
- Authors
Sauceda, John; Johnson, Mallory; Saberi, Parya
- Abstract
HIV + White, Latino, and African Americans ( N = 1131) completed a survey advertised on social media to re-examine the effect of depressive symptoms (via the Patient Health Questionnaire; PHQ-9) and race/ethnicity on antiretroviral therapy nonadherence (defined as past 3-month, 4-day treatment interruption). An adjusted logistic regression showed a 15 % increase in odds for a treatment interruption per 1-unit increase on the PHQ-9. The effect of depressive symptoms on nonadherence was greater for Latinos (OR = 1.80, p < 0.05), but not for African Americans, compared to Whites. The benefits of modern ART (e.g., simpler, forgiving to minor lapses) may not circumvent the effect of depressive symptomatology.
- Subjects
ANTIRETROVIRAL agents; BLACK people; MENTAL depression; DRUGS; ETHNIC groups; HISPANIC Americans; PATIENT compliance; QUESTIONNAIRES; RACE; WHITE people; LOGISTIC regression analysis; DESCRIPTIVE statistics; ODDS ratio
- Publication
AIDS & Behavior, 2016, Vol 20, Issue 11, p2624
- ISSN
1090-7165
- Publication type
Report
- DOI
10.1007/s10461-015-1283-8