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- Title
Multiple tracheobronchial mucosal lesions in two cases of Churg–Strauss syndrome.
- Authors
Matsushima, Hidekazu; Takayanagi, Noboru; Kurashima, Kazuyoshi; Tokunaga, Daido; Ubukata, Mikio; Kawabata, Yoshinori; Sugita, Yutaka
- Abstract
Churg–Strauss syndrome (CSS) is characterized by hypereosinophilia and a systemic necrotizing vasculitis seen almost exclusively in patients with asthma. The most common pathological findings in the chest in CSS are eosinophilic pneumonia, necrotizing vasculitis and granulomatous inflammation (extravascular granuloma). However, tracheobronchial mucosal lesions have rarely been reported in CSS. The authors report two patients with CSS who had multiple tracheobronchial mucosal lesions that were found by fibreoptic bronchoscopy. They were tiny nodular lesions and necrotizing bronchial inflammation with many eosinophils was observed upon pathological examination. The authors concluded that tracheobronchial mucosal lesions may be one of the manifestations of vasculitis seen in CSS.
- Subjects
CHURG-Strauss syndrome; CHRONIC granulomatous disease; EOSINOPHILIA; VASCULITIS; VASCULAR diseases; EOSINOPHILS
- Publication
Respirology, 2006, Vol 11, Issue 1, p109
- ISSN
1323-7799
- Publication type
Article
- DOI
10.1111/j.1440-1843.2006.00795.x