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- Title
Treatment Results of Endoscopic Transnasal Orbital Decompression for Graves' Orbitopathy—A Single-Center Retrospective Analysis in 28 Orbits of 16 Patients.
- Authors
Poślednik, Krzysztof B.; Czerwaty, Katarzyna; Ludwig, Nils; Molińska-Glura, Marta; Jabłońska-Pawlak, Anna; Miśkiewicz, Piotr; Kantor, Ireneusz; Dżaman, Karolina; Cyran, Anna M.; Szczepański, Mirosław J.
- Abstract
Graves' orbitopathy (GO) is an extrathyroidal manifestation of Graves' disease (GD), which can be associated with corneal ulcerations or optic neuropathy in severe forms. Transnasal endoscopic orbital decompression (TEOD) is a surgical procedure performed in order to decrease the intraorbital pressure by removing part of its bony borders in cases with excessive mass in orbit. The aim of this study was to present the results and evaluate the efficacy of TEOD for GO. The retrospective study included 28 orbits (16 patients) who underwent TEOD from 2017 to 2020. Outcome was evaluated based on visual acuity improvement, clinical activity score (CAS) decrease, proptosis, and intraocular pressure (IOP) reduction. A preoperative best-corrected visual acuity (BCVA) increased from 0.69 ± 0.385 (mean ± standard deviation) to 0.74 ± 0.332 (p = 0.17) postoperatively. CAS decreased in 15 orbits postoperatively. Proptosis decreased from 22.89 ± 1.873 mm to 21.25 ± 2.053 mm (p < 0.05). IOP decreased from a preoperative 16.11 ± 3.93 mmHg to 14.40 ± 3.27 mmHg (p < 0.05) postoperatively. In addition, postoperative relief of exposure keratitis was observed. The analysis of development of iatrogenic diplopia revealed increasing in degree of diplopia. TEOD shows rare complications, but significant improvements in BCVA, CAS, proptosis, and IOP.
- Subjects
ORBITS (Astronomy); VISUAL acuity; INTRAOCULAR pressure; RETROSPECTIVE studies; EXOPHTHALMOS
- Publication
Journal of Personalized Medicine, 2022, Vol 12, Issue 10, p1714
- ISSN
2075-4426
- Publication type
Article
- DOI
10.3390/jpm12101714