We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Age and Sex Differences in Rates of Influenza-Associated Hospitalizations in Hong Kong.
- Authors
Xi-Ling Wang; Lin Yang; Kwok-Hung Chan; King-Pan Chan; Pei-Hua Cao; Ho-Yin Lau, Eric; Malik Peiris, J. S.; Chit-Ming Wong
- Abstract
Few studies have explored age and sex differences in the disease burden of influenza, although men and women probably differ in their susceptibility to influenza infections. In this study, quasi-Poisson regression models were applied to weekly age- and sex-specific hospitalization numbers of pneumonia and influenza cases in the Hong Kong SAR, People's Republic of China, from 2004 to 2010. Age and sex differences were assessed by age- and sex-specific rates of excess hospitalization for influenza A subtypes A(H1N1), A(H3N2), and A(H1N1)pdm09 and influenza B, respectively. We found that, in children younger than 18 years, boys had a higher excess hospitalization rate than girls, with the male-to-female ratio of excess rate (MFR) ranging from 1.1 to 2.4. MFRs of hospitalization associated with different types/subtypes were less than 1.0 for adults younger than 40 years except for A(H3N2) (MFR = 1.6), while all the MFRs were equal to or higher than 1.0 in adults aged 40 years or more except for A(H1N1)pdm09 in elderly persons aged 65 years or more (MFR = 0.9). No MFR was found to be statistically significant (P<0.05) for hospitalizations associated with influenza type/subtype. There is some limited evidence on age and sex differences in hospitalization associated with influenza in the subtropical city of Hong Kong.
- Subjects
HONG Kong (China); INFLUENZA complications; INFLUENZA epidemiology; AGE distribution; CONFIDENCE intervals; HOSPITAL care; INFLUENZA A virus, H3N2 subtype; RESEARCH funding; RISK assessment; SEX distribution; INFLUENZA A virus, H1N1 subtype; DATA analysis software; DESCRIPTIVE statistics; ODDS ratio
- Publication
American Journal of Epidemiology, 2015, Vol 182, Issue 4, p335
- ISSN
0002-9262
- Publication type
Article
- DOI
10.1093/aje/kwv068