We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Hepatitis B infection is associated with periodontitis: the national health and nutrition examination survey (2009–2014).
- Authors
Chen, XianRun; Song, Jukun; Sun, JiangLing; Zhang, JiQin; Chen, XingJin; Zeng, ChongWen; Hu, JiaXin; Chang, XingTao; Jin, FuQian; Luo, SiYang; Chen, Zhu; Luo, Yi
- Abstract
Background: Current research has been inconclusive regarding whether hepatitis B infection is associated with an increased risk of periodontitis. This study aims to test the null hypothesis that no association exists between hepatitis B infection and an increased risk of periodontitis using the National Health and Nutrition Examination Survey (2009–2014). Methods: We performed a cross-sectional study using the National Health and Nutrition Examination Survey (NHANES) database (2009–2014) to assess the rate of the prevalence of periodontitis in patients with and without hepatitis B infection. Participants who had tested for hepatitis B and periodontitis were included. The included participants were divided into no/mild periodontitis and moderate/severe periodontitis groups according to their periodontal status. The association between hepatitis B infection and chronic periodontitis was evaluated by multivariable regression analyses adjusting for age, gender, race/ethnicity, education level, income-to-poverty ratio, smoking, alcohol, BMI, ALT, AST, creatinine, hypertension, and diabetes. Results: A total of 5957 participants were included and divided into two groups: inactive periodontitis group (n = 3444) and active periodontitis group (n = 2513). The results showed that participants with hepatitis B had a higher risk of periodontitis. After adjusting for covariables, adults with hepatitis B infection were 38% more likely to have periodontitis compared to those without hepatitis B infection (95% Confidence Interval [CI]:1.085–1.754). Conclusions: In general, the results suggest that CHB is positively associated with the more severe periodontitis. These results suggest that people with hepatitis B infection should take good periodontal care measures to avoid the occurrence and development of periodontitis.
- Subjects
RISK assessment; CROSS-sectional method; BODY mass index; CREATININE; RESEARCH funding; LOGISTIC regression analysis; SEX distribution; SMOKING; ASPARTATE aminotransferase; HYPERTENSION; CHRONIC hepatitis B; DISEASE prevalence; MULTIVARIATE analysis; AGE distribution; DESCRIPTIVE statistics; CHI-squared test; SURVEYS; RACE; ODDS ratio; HYPOTHESIS; ECONOMIC impact; ALANINE aminotransferase; ALCOHOLISM; CONFIDENCE intervals; DATA analysis software; PERIODONTITIS; DIABETES; DISEASE risk factors; DISEASE complications
- Publication
BMC Oral Health, 2024, Vol 24, Issue 1, p1
- ISSN
1472-6831
- Publication type
Article
- DOI
10.1186/s12903-024-04489-y