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- Title
Effect of Selenium and Selenoproteins on Radiation Resistance.
- Authors
Zhang, Shidi; Zhang, Guowei; Wang, Pengjie; Wang, Lianshun; Fang, Bing; Huang, Jiaqiang
- Abstract
With the advancement of radiological medicine and nuclear industry technology, radiation is increasingly used to diagnose human health disorders. However, large-scale nuclear leakage has heightened concerns about the impact on human organs and tissues. Selenium is an essential trace element that functions in the body mainly in the form of selenoproteins. Selenium and selenoproteins can protect against radiation by stimulating antioxidant actions, DNA repair functions, and immune enhancement. While studies on reducing radiation through antioxidants have been conducted for many years, the underlying mechanisms of selenium and selenoproteins as significant antioxidants in radiation damage mitigation remain incompletely understood. Therefore, this paper aims to provide new insights into developing safe and effective radiation protection agents by summarizing the anti-radiation mechanism of selenium and selenoproteins.
- Subjects
NF-kappa B; PROTEINS; SELENIUM; RADIATION injuries; GLYCOPROTEINS; CYSTEINE; OXIDATIVE stress; DNA; REACTIVE oxygen species; DNA damage; ANTIOXIDANTS; RADIATION-protective agents; GLUTATHIONE peroxidase; ETHANOLAMINES
- Publication
Nutrients, 2024, Vol 16, Issue 17, p2902
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu16172902