We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Odontogenic infections in the antibiotic era: approach to diagnosis, management, and prevention.
- Authors
Lou, Yiting; Sun, Zheyuan; Ma, Haiying; Cao, Danna; Sun, Mouyuan; Wang, Qianting; Wang, Jingyu; Zhuo, Qunhao; Tao, Ran; Ying, Binbin; Liu, Yu; Yu, Mengfei; Wang, Huiming
- Abstract
Purpose: The prevalence of odontogenic infections remains one of the highest in the world. If untreated, odontogenic infections can break through the limitation, disseminate to other organs or spaces, and cause high mortality rates. However, it is still difficult to rapidly target limited or disseminated infections in clinical practice. The type of disseminated odontogenic infections and the responsible bacteria have not been described in detail. Methods: Search databases (e.g., PubMed, MEDLINE, Web of Science, Embase) for reports published from 2018.1 to 2022.9. Use search strategies: ("odontogenic infections" OR "pulpitis" OR "periapical lesions" OR "periodontal diseases") AND ("disseminated infections" OR "complication"). Results: Fourteen different types of disseminated odontogenic infections, most of which are polymicrobial infections, can spread through the body either direct or through hematogenous diffusion. Multiple microbial infections can be more invasive in the transmission of infection. Secondary infections are commonly associated with bacteria like Fusobacterium spp., Streptococcus spp., Peptostreptococcus spp., Prevotella spp., and Staphylococcus spp. Antibiotics with broad-spectrum activity are fundamental as first-line antimicrobial agents based on the microorganisms isolated from disseminated infections. Conclusion: This review elaborates on the epidemiology, microorganisms, risk factors, and dissemination routes, and provides evidence-based opinions on the diagnosis, multidisciplinary management, and prevention of odontogenic infections for dentists and clinicians.
- Subjects
ANTIBIOTICS; ALLIED health education; DENTAL pathology prevention; INFECTION prevention; INFECTION risk factors; PREVENTION of communicable diseases; TERMS &; phrases; MICROBIAL sensitivity tests; DIAGNOSTIC imaging; INFECTION; DENTAL pathology; DENTISTS; CLINICAL pathology; INFECTIOUS disease transmission; EVIDENCE-based medicine; MIXED infections; HEALTH care teams; DISEASE risk factors; SYMPTOMS
- Publication
Infection, 2024, Vol 52, Issue 2, p301
- ISSN
0300-8126
- Publication type
Article
- DOI
10.1007/s15010-023-02117-5