We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Safety and efficacy of multilevel vertebroplasty for painful osteolytic spinal metastases: a single-centre experience.
- Authors
Zhang, Jian-Jun; Zhou, Yan; Hu, Hai-Yan; Sun, Yuan-Jue; Wang, Yong-Gang; Gu, Yi-Feng; Wu, Chun-Gen; Shen, Zan; Yao, Yang
- Abstract
<bold>Objective: </bold>To retrospectively assess the safety and efficacy of percutaneous vertebroplasty (PVP) for painful osteolytic spinal metastases when treating more than three vertebrae per session.<bold>Methods: </bold>A total of 153 patients with painful osteolytic spinal metastases underwent PVP. Group A patients (n = 93) underwent PVP at up to three vertebral levels per session. Group B patients (n = 60) underwent PVP at more than three levels in one session. Pain, quality of life (QoL), and mobility were assessed before and after PVP. Minor and major complications were systematically assessed.<bold>Results: </bold>Both groups experienced significant pain relief and QoL improvement after the intervention (p < 0.001). Mobility improvement was observed in both groups, despite worse mobility status before PVP in group B compared with group A. There was no significant difference between the two groups throughout the follow-up period in overall pain relief and improvement in QoL and mobility. There was also no significant difference between groups in minor and major complications.<bold>Conclusions: </bold>Multilevel vertebroplasty is safe and effective for the treatment of multiple osteolytic spinal metastases. Multilevel PVP relieves pain and improves QoL and mobility.<bold>Key Points: </bold>• Percutaneous vertebroplasty is safe and effective for painful osteolytic spinal metastases. • Multilevel vertebroplasty does not cause more complications than single-level vertebroplasty. • Multiple spinal metastases patients may regain functional independence after multilevel vertebroplasty.
- Subjects
VERTEBROPLASTY; SPINE diseases; METASTASIS; PAIN; QUALITY of life; PAIN management; BACKACHE; BONE resorption; COMPARATIVE studies; COMPUTED tomography; BONE fractures; RESEARCH methodology; MEDICAL cooperation; RESEARCH; SPINAL injuries; SPINAL tumors; EVALUATION research; PAIN measurement; RETROSPECTIVE studies; KARNOFSKY Performance Status; DISEASE complications
- Publication
European Radiology, 2017, Vol 27, Issue 8, p3436
- ISSN
0938-7994
- Publication type
journal article
- DOI
10.1007/s00330-016-4683-x