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- Title
Dynamic contrast-enhanced and ultra-high-resolution breast MRI at 7.0 Tesla.
- Authors
Stehouwer, Bertine; Klomp, Dennis; Bosch, Maurice; Korteweg, Mies; Gilhuijs, Kenneth; Witkamp, Arjen; Diest, Paul; Houwert, Karel; Kemp, Wybe; Luijten, Peter; Mali, W.; Veldhuis, Wouter
- Abstract
Objective: To assess the feasibility of 7-T contrast-enhanced breast MRI in patients with suspicious masses. Methods: Twenty patients with 23 suspicious breast masses on conventional imaging (mean size 13 mm, range 5-27 mm) were examined at 7 T. The MRI protocol included a dynamic series with injection of 0.1 mmol/kg gadobutrol (seven consecutive 3D T1-weighted gradient echo sequences, resolution 1 × 1 × 2 mm, temporal resolution 63 s) and ultra-high-resolution imaging (T1-weighted 3D gradient echo sequence, resolution 0.45 × 0.57 × 0.45 mm). Two observers (R1 and R2) independently judged the examinations on image quality and classified lesions according to BI-RADS. The added value of ultra-high-resolution imaging was assessed. Results: The image quality was deemed excellent in 1 and 0, good in 10 and 12, sufficient in 8 and 8, and insufficient in 1 and 0 for R1 and R2 respectively. Twenty of the 23 lesions were identified at 7-T MRI by both observers. All histopathologically proven malignant lesions ( n = 19) were identified and classified as BI-RADS-MRI 4 or 5. Ultra-high-resolution imaging increased reader confidence in 88 % (R1) and 59 % (R2) of acquisitions. Conclusion: The study shows the feasibility of dynamic contrast-enhanced 7-T breast MRI, where all malignant mass lesions were identified by two observers. Key Points: • Magnetic resonance imaging is important in the evaluation of breast cancer. • Recently, 7-T MRI has become available. • The 7-T dynamic contrast-enhanced breast MRI is feasible in patients. • The 7-T breast examinations are amenable to evaluation according to BI-RADS.
- Subjects
BREAST cancer patients; MAGNETIC resonance mammography; BREAST exams; FEASIBILITY studies; MAGNETIC resonance imaging of cancer
- Publication
European Radiology, 2013, Vol 23, Issue 11, p2961
- ISSN
0938-7994
- Publication type
Article
- DOI
10.1007/s00330-013-2985-9