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- Title
Serum ghrelin is associated with verbal learning and adiposity in a sample of healthy, fit older adults.
- Authors
Bellar, David; Glickman, Ellen L; Judge, Lawrence W; Gunstad, John
- Abstract
The purpose of the present investigation was to determine the relationship between serum ghrelin concentrations, adiposity, and verbal learning in a group of healthy, fit older adults. Participants were 28 healthy older adults (age: 70.8 ± 9.3 yrs, BMI: 27.3 ±5.7). Participants reported to the laboratory and basic anthropometric data were collected, followed by a blood draw to quantify serum ghrelin. Participants then underwent cognitive testing that included the revised Hopkins Verbal Learning Test (HVLT), as well as the Mini-Mental Status Exam (MMSE). The results of the MMSE test revealed that the volunteers were cognitively intact (MMSE 27.6 ± 1.8). A significant correlation emerged between serum ghrelin concentrations, 2 trials of the HVLT (Trial 1: r = 0.316, P = 0.05; Trial 2: r = 0.395, P = 0.03), and the sum of three-site skinfold analysis (r = 0.417, P = 0.015). Based upon the aforementioned relationships, it appears that fasting levels of serum ghrelin are related to both verbal learning and adiposity in healthy, fit older adults.
- Subjects
ADIPOSE tissue physiology; BIOMARKERS; HUMAN body composition; LEARNING; NEUROPSYCHOLOGICAL tests; PSYCHOLOGICAL tests; QUESTIONNAIRES; REFERENCE values; RESEARCH evaluation; GHRELIN
- Publication
BioMed Research International, 2013, Vol 2013, p202757
- ISSN
2314-6133
- Publication type
Journal Article
- DOI
2013/202757