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- Title
Contact sensitivity to quinidine sulfate from occupational exposure.
- Authors
Wainserg, Jan E.; Boman, Anders
- Abstract
Three workers exposed to quinidine sulfate became sensitized after short exposure times (2-3 months). They were patch test positive to quinidine in different vehicles, but negative to the diastereoisomer quinine. Guinea pig maximization tests demonstrated quinidine and quinine to be grade V allergens according to the classification of Magnusson & Kligman. When challenged for cross reactivity, the animals sensitive to quinine did not react to quinidine. Among the quinidine-sensitive guinea pigs, three of 20 (P > 0.05) reacted when challenged with quinine.
- Subjects
CONTACT dermatitis; QUINIDINE; QUININE sulfate; GUINEA pigs; DIASTEREOISOMERS; ALLERGENS
- Publication
Contact Dermatitis (01051873), 1981, Vol 7, Issue 1, p27
- ISSN
0105-1873
- Publication type
Article
- DOI
10.1111/j.1600-0536.1981.tb03955.x