We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Pharmacokinetics of lithium in the dog.
- Authors
ROSENTHAL, R. C.; KORITZ, G. D.; DAVIS, L. E.
- Abstract
The pharmacokinetics of lithium were determined in eight adult dogs. The data were fitted to a two-compartment model. Single intravenous doses of lithium chloride, and single oral doses of lithium carbonate were used. The mean plasma lithium half-life (l½) following the single intravenous dose was 21.6 h, and the mean apparent specific volume of distribution of the central compartment (V′c) was 0.189 l/kg. Mean bioavailability was 78.8% following oral administration.
- Publication
Journal of Veterinary Pharmacology & Therapeutics, 1986, Vol 9, Issue 1, p81
- ISSN
0140-7783
- Publication type
Article
- DOI
10.1111/j.1365-2885.1986.tb00015.x