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- Title
Uncommon Presentation of Granulomatosis with Polyangiitis Mimicking Metastatic Lung Cancer.
- Authors
Urbanska, Edyta Maria; Elversang, Johanna; Colville-Ebeling, Bonnie; Löfgren, Johan Olof; Nelveg-Kristensen, Karl Emil; Szpirt, Wladimir M.
- Abstract
Diagnosis of anomalous intrathoracic lesions may be challenging and require a multidisciplinary approach. We present a case of granulomatosis with polyangiitis (GPA) clinically and radiologically mimicking metastatic lung cancer with a bilateral pulmonary mass, mediastinal and cervical lymph node involvement, and pleural effusion. Surgical biopsy of the thoracic lesion revealed necrotic granulomatous inflammation, and the final diagnosis was subsequently confirmed by kidney biopsy and biochemical parameters. This case illustrates how comprehensive diagnosis secures timely and relevant treatment. Systemic vasculitis may be one of the key differential diagnoses in patients with multiorgan involvement, especially with pattern-mimicking lung cancer.
- Subjects
GRANULOMATOSIS with polyangiitis; METASTASIS; LUNG cancer; RENAL biopsy; PLEURAL effusions; LYMPH node cancer
- Publication
Clinics & Practice, 2021, Vol 11, Issue 2, p293
- ISSN
2039-7283
- Publication type
Article
- DOI
10.3390/clinpract11020042