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- Title
Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas.
- Authors
Fedele, Monica; Battista, Sabrina; Kenyon, Lawrence; Baldassarre, Gustavo; Fidanza, Vincenzo; Klein-Szanto, Andres J.P.; Parlow, A.F.; Visone, Rosa; Pierrantoni, Giovanna M.; Outwater, Eric; Santoro, Massimo; Croce, Carlo M.; Fusco, Alfredo
- Abstract
Presents a study which demonstrated that the overexpression of the high mobility group A2 (HMGA2) gene in transgenic mice leads to the onset of pituitary adenomas. Role of HMGA2 overexpression in human tumorigenesis; Generation of transgenic mice overexpressing the HMGA2 gene; Pathological findings in HMGA2 transgenic mice.
- Subjects
TRANSGENIC mice; PITUITARY tumors; ADENOMA; CARCINOGENESIS
- Publication
Oncogene, 2002, Vol 21, Issue 20, p3190
- ISSN
0950-9232
- Publication type
Article
- DOI
10.1038/sj.onc.1205428