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- Title
The use Platelet Rich Fibrin in dental implants: A literature review.
- Authors
Magalhães, Vandson Souza; Ribeiro, Rodrigo Alves; Barbosa Leite do Amaral, José Márcio; Pimentel, Angelica Castro; Paulim, Lilian Anami; Roman-Torres, Caio Vinicius G.
- Abstract
Background: Platelet rich fibrin (PRF) is a biomaterial derived from human blood, part of a platelet concentrate obtained through a centrifuge separating it. Its use is quite common in medicine and dentistry for recovery and healing in surgeries and for tissue regeneration. The aim of the present literature review was to evaluate the use of PRF in dentistry especially in the installation of dental implants. Material and methods: Articles published between 1997 and 2018 were evaluated in Pubmed, Scielo and Lilacs databases. were evaluated 128 articles, of these 18 evaluated the use of PRF and were used in this systematic review. Results: The main advantages and characteristics of PRF are: the acceleration of the cicatricial process of bones and gums in dental surgeries, especially in dental implants; high potential for tissue regeneration; PRF is capable of transforming adult stem cells into specific cells for the formation of bone and gingival tissues; ability to regenerate the tissue vascularization network. Some studies point to the use of PRF as a single fill material, others still show the use of PRF in combination with other bone graft materials. PRF can also be used as a membrane for guided bone regeneration, where the strong and elastic three-dimensional architecture acts as a saturable screen that will cover and stabilize the grafted material, protecting the material and the wound itself, allowing the gingival edges to approach and, consequently, favoring their re-epithelialization. Conclusion: We conclude that the applications of PRF are numerous, but a knowledge of biomaterial, efficiency and limitations are necessary for its use in daily practice.
- Subjects
GINGIVAL recession; OPERATIVE dentistry; BONE grafting; FIBRIN; DENTAL implants; DENTISTRY
- Publication
Trends in Transplantation, 2018, Vol 11, Issue 2, p1
- ISSN
1887-455X
- Publication type
Article
- DOI
10.15761/TiT.1000253