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- Title
Dietary Inflammatory Index and the Risk of Hyperuricemia: A Cross-Sectional Study in Chinese Adult Residents.
- Authors
Ye, Chen; Huang, Xiaojie; Wang, Ruoyu; Halimulati, Mairepaiti; Aihemaitijiang, Sumiya; Zhang, Zhaofeng
- Abstract
Background: Dietary Inflammatory Index (DII) scores have been consistently associated with several chronic diseases. This study explored the correlation between the DII and hyperuricemia in Chinese adult residents. Methods: The study included 7880 participants from the China Health and Nutrition Survey (CHNS), which was taken in in 2009. A 3-day 24 h meal review method was used to collect diet data and to calculate the DII score. Serum uric acid was obtained to determine hyperuricemia levels. Subjects were divided into a hyperuricemia group and a non-hyperuricemia group, according to their serum uric acid level. Multilevel logistic regression models were used to examine the association between DII scores and hyperuricemia. Results: After adjusting for covariates, a higher DII score was determined to be associated with a higher risk of hyperuricemia. Compared to those in the highest DII score group, the lower DII score group had an inverse association with hyperuricemia risk (Q2: 0.83, 95% CI: 0.70–0.99; Q3: 0.72, 95% CI: 0.60–0.86; Q4: 0.73, 95% CI: 0.61–0.88). The intake of energy-adjusted protein, total fat, MUFAs, PUFAs and saturated fatty acid was higher in the hyperuricemia group. Conclusions: A higher DII score is significantly associated with a higher risk of hyperuricemia. Controlling the intake of pro-inflammatory food may be beneficial to reduce the risk of hyperuricemia.
- Subjects
CHINA; BLOOD serum analysis; HYPERURICEMIA; UNSATURATED fatty acids; DIET in disease; CONFIDENCE intervals; FAT content of food; INFLAMMATION; CROSS-sectional method; SATURATED fatty acids; DIET; INGESTION; RISK assessment; COMPARATIVE studies; DIET therapy; DESCRIPTIVE statistics; OMEGA-3 fatty acids; URIC acid; LOGISTIC regression analysis; STATISTICAL models; DIETARY proteins; ALGORITHMS; DISEASE risk factors; ADULTS
- Publication
Nutrients, 2021, Vol 13, Issue 12, p4504
- ISSN
2072-6643
- Publication type
Article
- DOI
10.3390/nu13124504