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- Title
Memede filloid tümörü olan hastaların analizi.
- Authors
Atalay, Can; Kınaş, Volkan; Çelebioğlu, Sait
- Abstract
Objective: The diagnosis and management of phylloides tumors is challenging due to its low incidence. The treatment of these tumors is surgery, however the extent of surgery, the application of adjuvant chemotherapy and radiotherapy are still controversial. Therefore, we aimed to evaluate patients who were treated with a diagnosis of phylloides tumor of the breast in our clinic. Material and Methods: Patients who were treated with a diagnosis of phylloides tumor of the breast between June 2011 and June 2013 were reviewed retrospectively. Patient demographic characteristics (age, gender), menopausal status, symptoms, radiologic and surgical methods used for diagnosis and treatment, histopathologic features of the tumor and type of adjuvant therapy were evaluated. Patients were grouped as benign or borderline/malignant according to histopathological diagnosis. Patients in these groups were compared in terms of age, menopausal status, tumor size and the number of mitosis within the tumor. Results: The median age was 26 years (17-59), and 30 patients were female. The surgical treatment of choice was wide local excision with tumor-free surgical margins in 29 patients and mastectomy in one patient. Histopathological diagnosis after surgery was benign in 21 patients (70%), borderline in 6 patients (20%) and malignant phylloides tumor in 3 patients (10%). Patients with borderline and malignant phylloides tumors were significantly older (p=0.002) and had higher mitotic counts (p<0.0001). There was no significant relationship between histopathologic subtypes of phylloides tumors and menopausal status (p=0.06) or tumor size (p=0.1). Conclusion: Surgery is the treatment of choice for phylloides tumors, and obtaining tumor-free margins is important. Since phylloides tumors might recur as borderline/malignant tumors, local control with surgery and adjuvant radiotherapy should be provided when required. In this way, distant metastases and death that may arise due to possible malignant recurrences might be avoided.
- Publication
Turkish Journal of Surgery / Ulusal Cerrahi Dergisi, 2014, Vol 30, Issue 3, p129
- ISSN
1300-0705
- Publication type
Article
- DOI
10.5152/UCD.2014.2719