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Caveolin-1 deficiency induces a MEK- ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis.
Published in:
EMBO Molecular Medicine, 2015, v. 7, n. 3, p. 357, doi. 10.15252/emmm.201570010
By:
- Strippoli, Raffaele;
- Loureiro, Jesús;
- Moreno, Vanessa;
- Benedicto, Ignacio;
- Lozano, María Luisa Pérez;
- Barreiro, Olga;
- Pellinen, Teijo;
- Minguet, Susana;
- Foronda, Miguel;
- Osteso, Maria Teresa;
- Calvo, Enrique;
- Vázquez, Jesús;
- Cabrera, Manuel López;
- del Pozo, Miguel Angel
Publication type:
Article
Caveolin-1 deficiency induces a MEK- ERK1/2-Snail-1-dependent epithelial-mesenchymal transition and fibrosis during peritoneal dialysis.
Published in:
EMBO Molecular Medicine, 2015, v. 7, n. 1, p. 102, doi. 10.15252/emmm.201404127
By:
- Strippoli, Raffaele;
- Loureiro, Jesús;
- Moreno, Vanessa;
- Benedicto, Ignacio;
- Pérez Lozano, María Luisa;
- Barreiro, Olga;
- Pellinen, Teijo;
- Minguet, Susana;
- Foronda, Miguel;
- Osteso, Maria Teresa;
- Calvo, Enrique;
- Vázquez, Jesús;
- López Cabrera, Manuel;
- Pozo, Miguel Angel
Publication type:
Article
ROR1-STAT3 signaling contributes to ovarian cancer intra-tumor heterogeneity.
Published in:
Cell Death Discovery, 2023, v. 9, n. 1, p. 1, doi. 10.1038/s41420-023-01527-6
By:
- Piki, Emilia;
- Dini, Alice;
- Raivola, Juuli;
- Salokas, Kari;
- Zhang, Kaiyang;
- Varjosalo, Markku;
- Pellinen, Teijo;
- Välimäki, Katja;
- Veskimäe, Kristina Tabor;
- Staff, Synnöve;
- Hautaniemi, Sampsa;
- Murumägi, Astrid;
- Ungureanu, Daniela
Publication type:
Article
Inhibition of Transforming Growth Factor-Activated Kinase 1 (TAK1) Blocks and Reverses Epithelial to Mesenchymal Transition of Mesothelial Cells.
Published in:
PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031492
By:
- Strippoli, Raffaele;
- Benedicto, Ignacio;
- Lozano, Maria Luisa Perez;
- Pellinen, Teijo;
- Sandoval, Pilar;
- Lopez-Cabrera, Manuel;
- del Pozo, Miguel Angel
Publication type:
Article
Prognostic Impact of Tumor-Associated Macrophages on Survival Is Checkpoint Dependent in Classical Hodgkin Lymphoma.
Published in:
Cancers, 2020, v. 12, n. 4, p. 877, doi. 10.3390/cancers12040877
By:
- Karihtala, Kristiina;
- Leivonen, Suvi-Katri;
- Brück, Oscar;
- Karjalainen-Lindsberg, Marja-Liisa;
- Mustjoki, Satu;
- Pellinen, Teijo;
- Leppä, Sirpa
Publication type:
Article
Adverse prognostic impact of regulatory T‐cells in testicular diffuse large B‐cell lymphoma.
Published in:
European Journal of Haematology, 2020, v. 105, n. 6, p. 712, doi. 10.1111/ejh.13484
By:
- Pollari, Marjukka;
- Pellinen, Teijo;
- Karjalainen‐Lindsberg, Marja‐Liisa;
- Kellokumpu‐Lehtinen, Pirkko‐Liisa;
- Leivonen, Suvi‐Katri;
- Leppä, Sirpa
Publication type:
Article
E-cadherin is a robust prognostic biomarker in colorectal cancer and low expression is associated with sensitivity to inhibitors of topoisomerase, aurora, and HSP90 in preclinical models.
Published in:
Molecular Oncology, 2022, v. 16, n. 12, p. 2312, doi. 10.1002/1878-0261.13159
By:
- Bruun, Jarle;
- Eide, Peter W.;
- Holst Bergsland, Christian;
- Bruck, Oscar;
- Svindland, Aud;
- Arjama, Mariliina;
- Välimäki, Katja;
- Bjørnslett, Merete;
- Guren, Marianne G.;
- Kallioniemi, Olli;
- Nesbakken, Arild;
- Lothe, Ragnhild A.;
- Pellinen, Teijo
Publication type:
Article
Prognostic, predictive, and pharmacogenomic assessments of CDX2 refine stratification of colorectal cancer.
Published in:
Molecular Oncology, 2018, v. 12, n. 9, p. 1639, doi. 10.1002/1878-0261.12347
By:
- Bruun, Jarle;
- Sveen, Anita;
- Barros, Rita;
- Eide, Peter W.;
- Eilertsen, Ina;
- Kolberg, Matthias;
- Pellinen, Teijo;
- David, Leonor;
- Svindland, Aud;
- Kallioniemi, Olli;
- Guren, Marianne G.;
- Nesbakken, Arild;
- Almeida, Raquel;
- Lothe, Ragnhild A.
Publication type:
Article
Low nuclear expression of HIF‐hydroxylases PHD2/EGLN1 and PHD3/EGLN3 are associated with poor recurrence‐free survival in clear cell renal cell carcinoma.
Published in:
Cancer Medicine, 2024, v. 13, n. 3, p. 1, doi. 10.1002/cam4.6998
By:
- Luomala, Lassi;
- Mattila, Kalle;
- Vainio, Paula;
- Nisén, Harry;
- Pellinen, Teijo;
- Lohi, Jouni;
- Laajala, Teemu D.;
- Järvinen, Petrus;
- Koskenniemi, Anna‐Riina;
- Jaakkola, Panu;
- Mirtti, Tuomas
Publication type:
Article
SHARPIN is an endogenous inhibitor of ?1-integrin activation.
Published in:
Nature Cell Biology, 2011, v. 13, n. 11, p. 1315, doi. 10.1038/ncb2340
By:
- Rantala, Juha K.;
- Pouwels, Jeroen;
- Pellinen, Teijo;
- Veltel, Stefan;
- Laasola, Petra;
- Mattila, Elina;
- Potter, Christopher S.;
- Duffy, Ted;
- Sundberg, John P.;
- Kallioniemi, Olli;
- Askari, Janet A.;
- Humphries, Martin J.;
- Parsons, Maddy;
- Salmi, Marko;
- Ivaska, Johanna
Publication type:
Article
Negative regulation of EGFR signalling through integrin-a<sub>1</sub>ß<sub>1</sub>-mediated activation of protein tyrosine phosphatase TCPTP.
Published in:
Nature Cell Biology, 2005, v. 7, n. 1, p. 78, doi. 10.1038/ncb1209
By:
- Mattila, Elina;
- Pellinen, Teijo;
- Nevo, Jonna;
- Vuoriluoto, Karoliina;
- Arjonen, Antti;
- Ivaska, Johanna
Publication type:
Article
Cancer‐associated fibroblast activation predicts progression, metastasis, and prognosis of cutaneous squamous cell carcinoma.
Published in:
International Journal of Cancer, 2024, v. 155, n. 6, p. 1112, doi. 10.1002/ijc.34957
By:
- Knuutila, Jaakko S.;
- Riihilä, Pilvi;
- Nissinen, Liisa;
- Heiskanen, Lauri;
- Kallionpää, Roosa E.;
- Pellinen, Teijo;
- Kähäri, Veli‐Matti
Publication type:
Article
Distinct molecular profiles and shared drug vulnerabilities in pancreatic metastases of renal cell carcinoma.
Published in:
Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07004-9
By:
- Roos-Mattila, Matilda;
- Kallio, Pauliina;
- Luck, Tamara J.;
- Polso, Minttu;
- Kumari, Romika;
- Mikkonen, Piia;
- Välimäki, Katja;
- Malmstedt, Minna;
- Ellonen, Pekka;
- Pellinen, Teijo;
- Heckman, Caroline A.;
- Mustonen, Harri;
- Puolakkainen, Pauli A.;
- Alitalo, Kari;
- Kallioniemi, Olli;
- Mirtti, Tuomas;
- Rannikko, Antti S.;
- Pietiäinen, Vilja M.;
- Seppänen, Hanna E.
Publication type:
Article
Distinct molecular profiles and shared drug vulnerabilities in pancreatic metastases of renal cell carcinoma.
Published in:
Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07004-9
By:
- Roos-Mattila, Matilda;
- Kallio, Pauliina;
- Luck, Tamara J.;
- Polso, Minttu;
- Kumari, Romika;
- Mikkonen, Piia;
- Välimäki, Katja;
- Malmstedt, Minna;
- Ellonen, Pekka;
- Pellinen, Teijo;
- Heckman, Caroline A.;
- Mustonen, Harri;
- Puolakkainen, Pauli A.;
- Alitalo, Kari;
- Kallioniemi, Olli;
- Mirtti, Tuomas;
- Rannikko, Antti S.;
- Pietiäinen, Vilja M.;
- Seppänen, Hanna E.
Publication type:
Article
Fibroblast as a critical stromal cell type determining prognosis in prostate cancer.
Published in:
Prostate, 2019, v. 79, n. 13, p. 1505, doi. 10.1002/pros.23867
By:
- Blom, Sami;
- Erickson, Andrew;
- Östman, Arne;
- Rannikko, Antti;
- Mirtti, Tuomas;
- Kallioniemi, Olli;
- Pellinen, Teijo
Publication type:
Article
Competitive binding of Rab21 and p120RasGAP to integrins regulates receptor traffic and migration.
Published in:
Journal of Cell Biology, 2011, v. 194, n. 2, p. 291, doi. 10.1083/jcb.201012126
By:
- Mai, Anja;
- Veltel, Stefan;
- Pellinen, Teijo;
- Padzik, Artur;
- Coffey, Eleanor;
- Marjomäki, Varpu;
- Ivaska, Johanna
Publication type:
Article
Small GTPase Rab21 regulates cell adhesion and controls endosomal traffic of 131-integrins.
Published in:
Journal of Cell Biology, 2006, v. 173, n. 5, p. 767, doi. 10.1083/jcb.200509019
By:
- Pellinen, Teijo;
- Arjonen, Antti;
- Vuoriluoto, Karoliina;
- Kallio, Katja;
- Fransen, Jack A. M.;
- Ivaska, Johanna
Publication type:
Article
Clonal heterogeneity influences drug responsiveness in renal cancer assessed by ex vivo drug testing of multiple patient‐derived cancer cells.
Published in:
International Journal of Cancer, 2019, v. 144, n. 6, p. 1356, doi. 10.1002/ijc.31815
By:
- Saeed, Khalid;
- Ojamies, Poojitha;
- Pellinen, Teijo;
- Eldfors, Samuli;
- Turkki, Riku;
- Lundin, Johan;
- Järvinen, Petrus;
- Nisen, Harry;
- Taari, Kimmo;
- af Hällström, Taija M.;
- Rannikko, Antti;
- Mirtti, Tuomas;
- Kallioniemi, Olli;
- Östling, Päivi
Publication type:
Article
Drug response profiles in patient-derived cancer cells across histological subtypes of ovarian cancer: real-time therapy tailoring for a patient with low-grade serous carcinoma.
Published in:
British Journal of Cancer, 2023, v. 128, n. 4, p. 678, doi. 10.1038/s41416-022-02067-z
By:
- Murumägi, Astrid;
- Ungureanu, Daniela;
- Khan, Suleiman;
- Arjama, Mariliina;
- Välimäki, Katja;
- Ianevski, Aleksandr;
- Ianevski, Philipp;
- Bergström, Rebecka;
- Dini, Alice;
- Kanerva, Anna;
- Koivisto-Korander, Riitta;
- Tapper, Johanna;
- Lassus, Heini;
- Loukovaara, Mikko;
- Mägi, Andrus;
- Hirasawa, Akira;
- Aoki, Daisuke;
- Pietiäinen, Vilja;
- Pellinen, Teijo;
- Bützow, Ralf
Publication type:
Article
High tumor cell platelet‐derived growth factor receptor beta expression is associated with shorter survival in malignant pleural epithelioid mesothelioma.
Published in:
Journal of Pathology: Clinical Research, 2021, v. 7, n. 5, p. 482, doi. 10.1002/cjp2.218
By:
- Ollila, Hely;
- Paajanen, Juuso;
- Wolff, Henrik;
- Ilonen, Ilkka;
- Sutinen, Eva;
- Välimäki, Katja;
- Östman, Arne;
- Anttila, Sisko;
- Kettunen, Eeva;
- Räsänen, Jari;
- Kallioniemi, Olli;
- Myllärniemi, Marjukka;
- Mäyränpää, Mikko I;
- Pellinen, Teijo
Publication type:
Article
Combined epithelial marker analysis of tumour budding in stage II colorectal cancer.
Published in:
Journal of Pathology: Clinical Research, 2019, v. 5, n. 1, p. 63, doi. 10.1002/cjp2.119
By:
- Slik, Khadija;
- Blom, Sami;
- Turkki, Riku;
- Välimäki, Katja;
- Kurki, Samu;
- Mustonen, Harri;
- Haglund, Caj;
- Carpén, Olli;
- Kallioniemi, Olli;
- Korkeila, Eija;
- Sundström, Jari;
- Pellinen, Teijo
Publication type:
Article
SMO Inhibition Modulates Cellular Plasticity and Invasiveness in Colorectal Cancer.
Published in:
Frontiers in Pharmacology, 2018, p. 1, doi. 10.3389/fphar.2017.00956
By:
- Magistri, Paolo;
- Battistelli, Cecilia;
- Strippoli, Raffaele;
- Petrucciani, Niccolò;
- Pellinen, Teijo;
- Rossi, Lucia;
- Mangogna, Livia;
- Aurello, Paolo;
- D'Angelo, Francesco;
- Tripodi, Marco;
- Ramacciato, Giovanni;
- Nigri, Giuseppe
Publication type:
Article
A simple heterogeneous one-step assay for screening estrogenic compounds.
Published in:
Biotechnology Letters, 2013, v. 35, n. 1, p. 47, doi. 10.1007/s10529-012-1050-0
By:
- Huovinen, Tuomas;
- Rytkönen, Kalle;
- Lamminmäki, Urpo;
- Pellinen, Teijo
Publication type:
Article
Prognostic Role of Tumor Immune Microenvironment in Pleural Epithelioid Mesothelioma.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.870352
By:
- Ollila, Hely;
- Mäyränpää, Mikko I.;
- Paavolainen, Lassi;
- Paajanen, Juuso;
- Välimäki, Katja;
- Sutinen, Eva;
- Wolff, Henrik;
- Räsänen, Jari;
- Kallioniemi, Olli;
- Myllärniemi, Marjukka;
- Ilonen, Ilkka;
- Pellinen, Teijo
Publication type:
Article
Fibroblast subsets in non-small cell lung cancer: Associations with survival, mutations, and immune features.
Published in:
JNCI: Journal of the National Cancer Institute, 2023, v. 115, n. 1, p. 71, doi. 10.1093/jnci/djac178
By:
- Pellinen, Teijo;
- Paavolainen, Lassi;
- Martín-Bernabé, Alfonso;
- Araujo, Renata Papatella;
- Strell, Carina;
- Mezheyeuski, Artur;
- Backman, Max;
- Fleur, Linnea La;
- Brück, Oscar;
- Sjölund, Jonas;
- Holmberg, Erik;
- Välimäki, Katja;
- Brunnström, Hans;
- Botling, Johan;
- Moreno-Ruiz, Pablo;
- Kallioniemi, Olli;
- Micke, Patrick;
- Östman, Arne
Publication type:
Article

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