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- Title
Copper-Catalyzed N- and O-Arylation of Amides: Alternative Approaches to 3,4-Dihydroquinolin-2-ones, Quinolin-2-ones, and 12 H-Chromeno[2,3- b]quinolin-12-ones.
- Authors
Zhang, Xinying; Guo, Xiaojie; Fang, Liangliang; Song, Yunping; Fan, Xuesen
- Abstract
The efficient syntheses of 3-cyanoquinolin-2-ones, 3-(2-bromobenzyl)-3-cyano-3,4-dihydroquinolin-2-ones, 3-(2-bromobenzyl)quinolin-2-ones, and 12 H-chromeno[2,3- b]quinolin-12-ones through copper-catalyzed N- and O-arylation of amides by using readily available 2-bromobenzyl bromides and cyanoacetamides as starting materials were developed.
- Subjects
AMIDE synthesis; ARYLATION; AROMATIC compound synthesis; BRETYLIUM tosylate
- Publication
European Journal of Organic Chemistry, 2013, Vol 2013, Issue 36, p8087
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.201301373