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- Title
Severe Acute Respiratory Syndrome Coronavirus 2 Adaptive Immunity in Nursing Home Residents Following a Third Dose of the Comirnaty Coronavirus Disease 2019 Vaccine.
- Authors
Giménez, Estela; Albert, Eliseo; Zulaica, Joao; Torres, Ignacio; Rusu, Luciana; Moreno, Alicia Rodríguez; Burgos, Javier S; Peiró, Salvador; Salas, Dolores; Vanaclocha, Hermelinda; Limón, Ramón; Alcaraz, María Jesús; Sánchez-Payá, José; Díez-Domingo, Javier; Comas, Iñaki; Gonzáles-Candelas, Fernando; Geller, Ron; Navarro, David; Group, Valencian Vaccine Research Program (ProVaVac) Study
- Abstract
A third Comirnaty vaccine dose increased severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) receptor-binding domain antibody levels (median, 93-fold) and neutralizing antibody titers against Wuhan-Hu-1 (median, 57-fold), Beta (me 22-fold), Delta, (median, 43-fold), and Omicron (median, 8-fold) variants, but had less impact on S-reactive T-cell immunity in nursing home residents.
- Subjects
COVID-19; GENETIC mutation; COVID-19 vaccines; T cells; CELLULAR immunity; VIRAL antibodies
- Publication
Clinical Infectious Diseases, 2022, Vol 75, Issue 1, pe865
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/ciac223