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Alternatives to amyloid for Alzheimer's disease therapies—a symposium report.
Published in:
Annals of the New York Academy of Sciences, 2020, v. 1475, n. 1, p. 3, doi. 10.1111/nyas.14371
By:
- Cable, Jennifer;
- Holtzman, David M.;
- Hyman, Bradley T.;
- Tansey, Malú Gámez;
- Colonna, Marco;
- Kellis, Manolis;
- Brinton, Roberta D.;
- Albert, Marilyn;
- Wellington, Cheryl L.;
- Sisodia, Sangram S.;
- Tanzi, Rudolph E.
Publication type:
Article
Energy-dependent volume regulation in primary cultured cerebral astrocytes.
Published in:
Journal of Cellular Physiology, 1986, v. 128, n. 2, p. 209, doi. 10.1002/jcp.1041280211
By:
- Olson, James E.;
- Sankar, Raman;
- Holtzman, David;
- James, Adrian;
- Fleischhacker, Deborah
Publication type:
Article
INCIDENCE OF HIGH GRADE QTCF PROLONGATION AND ITS MANAGEMENT AMONG PATIENTS UNDERGOING TREATMENT FOR DRUG RESISTANT TUBERCULOSIS (DR-TB): CASE SERIES.
Published in:
African Journal of Infectious Diseases, 2021, v. 15, p. 38, doi. 10.21010/ajidv15i2S.5
By:
- Asfaw, Meseret T.;
- Holtzman, David L.;
- Kwan, Gene F.;
- Oyewusi, Lawrence T.;
- Mitnick, Carole D.;
- Seung, Kwonjune J.
Publication type:
Article
Gut Microbiota: From the Forgotten Organ to a Potential Key Player in the Pathology of Alzheimer's Disease.
Published in:
2020
By:
- Seo, Dong-Oh;
- Holtzman, David M
Publication type:
journal article
Corpora amylacea are associated with tau burden and cognitive status in Alzheimer's disease.
Published in:
Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01409-5
By:
- Wander, Connor M.;
- Tsujimoto, Tamy Harumy Moraes;
- Ervin, John F.;
- Wang, Chanung;
- Maranto, Spencer M.;
- Bhat, Vanya;
- Dallmeier, Julian D.;
- Wang, Shih-Hsiu Jerry;
- Lin, Feng-Chang;
- Scott, William K.;
- Holtzman, David M.;
- Cohen, Todd J.
Publication type:
Article
STAT3 inhibitor mitigates cerebral amyloid angiopathy and parenchymal amyloid plaques while improving cognitive functions and brain networks.
Published in:
Acta Neuropathologica Communications, 2021, v. 9, n. 1, p. 1, doi. 10.1186/s40478-021-01293-5
By:
- Mehla, Jogender;
- Singh, Itender;
- Diwan, Deepti;
- Nelson, James W.;
- Lawrence, Molly;
- Lee, Eunjae;
- Bauer, Adam Q.;
- Holtzman, David M.;
- Zipfel, Gregory J.
Publication type:
Article
Validating Predicted Biological Effects of Alzheimer's Disease Associated SNPs Using CSF Biomarker Levels.
Published in:
Journal of Alzheimer's Disease, 2010, v. 21, n. 3, p. 833, doi. 10.3233/JAD-2010-091711
By:
- Kauwe, John S. K.;
- Cruchaga, Carlos;
- Bertelsen, Sarah;
- Mayo, Kevin;
- Latu, Wayne;
- Nowotny, Petra;
- Hinrichs, Anthony L.;
- Fagan, Anne M.;
- Holtzman, David M.;
- Goate, Alison M.
Publication type:
Article
Caffeine Suppresses Amyloid-β Levels in Plasma and Brain of Alzheimer's Disease Transgenic Mice.
Published in:
Journal of Alzheimer's Disease, 2009, v. 17, n. 3, p. 681, doi. 10.3233/JAD-2009-1071
By:
- Chuanhai Cao;
- Cirrito, John R.;
- Xiaoyang Lin;
- Wang, Lilly;
- Verges, Deborah K;
- Dickson, Alexander;
- Mamcarz, Malgorzata;
- Chi Zhang;
- Mori, Takashi;
- Arendash, Gary W.;
- Holtzman, David M.;
- Potter, Huntington
Publication type:
Article
The search for antecedent biomarkers of Alzheimer's disease.
Published in:
Journal of Alzheimer's Disease, 2005, v. 8, n. 4, p. 347
By:
- Fagan, Anne M.;
- Csernansky, Cynthia A.;
- Morris, John C.;
- Holtzman, David M.
Publication type:
Article
High‐affinity interactions and signal transduction between Aβ oligomers and TREM2.
Published in:
EMBO Molecular Medicine, 2018, v. 10, n. 11, p. N.PAG, doi. 10.15252/emmm.201809027
By:
- Lessard, Christian B;
- Malnik, Samuel L;
- Zhou, Yingyue;
- Ladd, Thomas B;
- Cruz, Pedro E;
- Ran, Yong;
- Mahan, Thomas E;
- Chakrabaty, Paramita;
- Holtzman, David M;
- Ulrich, Jason D;
- Colonna, Marco;
- Golde, Todd E
Publication type:
Article
CSF sTREM2: marking the tipping point between preclinical AD and dementia?
Published in:
EMBO Molecular Medicine, 2016, v. 8, n. 5, p. 437, doi. 10.15252/emmm.201606245
By:
- Schindler, Suzanne E;
- Holtzman, David M
Publication type:
Article
Cerebrospinal fluid tau and ptau181 increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease.
Published in:
EMBO Molecular Medicine, 2009, v. 1, n. 8/9, p. 371, doi. 10.1002/emmm.200900048
By:
- Fagan, Anne M.;
- Mintun, Mark A.;
- Shah, Aarti R.;
- Aldea, Patricia;
- Roe, Catherine M.;
- Mach, Robert H.;
- Marcus, Daniel;
- Morris, John C.;
- Holtzman, David M.
Publication type:
Article
A surrogate marker for Aβ42 production in the CNS.
Published in:
EMBO Molecular Medicine, 2009, v. 1, n. 4, p. 195, doi. 10.1002/emmm.200900030
By:
- Holtzman, David M.
Publication type:
Article
Incorporation of 3H-thymidine in telencephalic structures of the vomeronasal and olfactory systems of embryonic garter snakes.
Published in:
Journal of Comparative Neurology, 1991, v. 304, n. 3, p. 450, doi. 10.1002/cne.903040309
By:
- Holtzman, David A.;
- Halpern, Mimi
Publication type:
Article
Incorporation of 3H-thymidine in the embryonic vomeronasal and olfactory epithelia of garter snakes.
Published in:
Journal of Comparative Neurology, 1991, v. 304, n. 3, p. 435, doi. 10.1002/cne.903040308
By:
- Holtzman, David A.;
- Halpern, Mimi
Publication type:
Article
Proteomic clusters underlie heterogeneity in preclinical Alzheimer's disease progression.
Published in:
Brain: A Journal of Neurology, 2023, v. 146, n. 7, p. 2944, doi. 10.1093/brain/awac484
By:
- Wisch, Julie K;
- Butt, Omar H;
- Gordon, Brian A;
- Schindler, Suzanne E;
- Fagan, Anne M;
- Henson, Rachel L;
- Yang, Chengran;
- Boerwinkle, Anna H;
- Benzinger, Tammie L S;
- Holtzman, David M;
- Morris, John C;
- Cruchaga, Carlos;
- Ances, Beau M
Publication type:
Article
Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes.
Published in:
2022
By:
- Long, Justin M;
- Coble, Dean W;
- Xiong, Chengjie;
- Schindler, Suzanne E;
- Perrin, Richard J;
- Gordon, Brian A;
- Benzinger, Tammie L S;
- Grant, Elizabeth;
- Fagan, Anne M;
- Harari, Oscar;
- Cruchaga, Carlos;
- Holtzman, David M;
- Morris, John C
Publication type:
journal article
Sleep and longitudinal cognitive performance in preclinical and early symptomatic Alzheimer's disease.
Published in:
2021
By:
- Lucey, Brendan P;
- Wisch, Julie;
- Boerwinkle, Anna H;
- Landsness, Eric C;
- Toedebusch, Cristina D;
- McLeland, Jennifer S;
- Butt, Omar H;
- Hassenstab, Jason;
- Morris, John C;
- Ances, Beau M;
- Holtzman, David M
Publication type:
journal article
Incident cognitive impairment: longitudinal changes in molecular, structural and cognitive biomarkers.
Published in:
2018
By:
- Roe, Catherine M;
- Ances, Beau M;
- Head, Denise;
- Babulal, Ganesh M;
- Stout, Sarah H;
- Grant, Elizabeth A;
- Hassenstab, Jason;
- Xiong, Chengjie;
- Holtzman, David M;
- Benzinger, Tammie L S;
- Schindler, Suzanne E;
- Fagan, Anne M;
- Morris, John C
Publication type:
journal article
Longitudinal brain imaging in preclinical Alzheimer disease: impact of APOE ε4 genotype.
Published in:
2018
By:
- Mishra, Shruti;
- Blazey, Tyler M.;
- Holtzman, David M.;
- Cruchaga, Carlos;
- Yi Su;
- Morris, John C.;
- Benzinger, Tammie L. S.;
- Gordon, Brian A.;
- Su, Yi
Publication type:
journal article
Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levels.
Published in:
2017
By:
- Ju, Yo-El S.;
- Ooms, Sharon J.;
- Sutphen, Courtney;
- Macauley, Shannon L.;
- Zangrilli, Margaret A.;
- Jerome, Gina;
- Fagan, Anne M.;
- Mignot, Emmanuel;
- Zempel, John M.;
- Claassen, Jurgen A. H. R.;
- Holtzman, David M.
Publication type:
journal article
The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging.
Published in:
2016
By:
- Gordon, Brian A.;
- Friedrichsen, Karl;
- Brier, Matthew;
- Blazey, Tyler;
- Yi Su;
- Christensen, Jon;
- Aldea, Patricia;
- McConathy, Jonathan;
- Holtzman, David M.;
- Cairns, Nigel J.;
- Morris, John C.;
- Fagan, Anne M.;
- Ances, Beau M.;
- Benzinger, Tammie L. S.;
- Su, Yi
Publication type:
journal article
Clusterin contributes to caspase-3?independent brain injury following neonatal hypoxia-ischemia.
Published in:
Nature Medicine, 2001, v. 7, n. 3, p. 338, doi. 10.1038/85487
By:
- Han, Byung Hee;
- DeMattos, Ronald B.;
- Dugan, Laura L.;
- Kim-Han, Jeong Sook;
- Brendza, Robert P.;
- Fryer, John D.;
- Kierson, Malca;
- Cirrito, John;
- Quick, Kevin;
- Harmony, Judith A. K.;
- Aronow, Bruce J.;
- Holtzman, David M.
Publication type:
Article
Clearance of amyloid b-peptide from brain: transport or metabolism?
Published in:
Nature Medicine, 2000, v. 6, n. 7, p. 718, doi. 10.1038/77397
By:
- Zlokovic, Berislav V.;
- Yamada, Shinya;
- Holtzman, David;
- Ghiso, Jorge;
- Frangione, Blas
Publication type:
Article
Symposium: What Does the Microbiome Tell Us about Prevention and Treatment of AD/ADRD?
Published in:
Journal of Neuroscience, 2024, v. 44, n. 41, p. 1, doi. 10.1523/JNEUROSCI.1295-24.2024
By:
- Capocchi, Joia K.;
- Figueroa-Romero, Claudia;
- Dunham, Sage J. B.;
- Faraci, Gina;
- Rothman, Jason A.;
- Whiteson, Katrine L.;
- Seo, Dong-oh;
- Holtzman, David M.;
- Grabrucker, Stefanie;
- Nolan, Yvonne M.;
- Kaddurah-Daouk, Rima;
- Jett, David A.
Publication type:
Article
In Vivo Assessment of Brain Interstitial Fluid with Microdialysis Reveals Plaque-Associated Changes in Amyloid-β Metabolism and Half-Life.
Published in:
Journal of Neuroscience, 2003, v. 23, n. 26, p. 8844, doi. 10.1523/JNEUROSCI.23-26-08844.2003
By:
- Cirrito, John R.;
- May, Patrick C.;
- O'Dell, Mark A.;
- Taylor, Jennie W.;
- Parsadanian, Maia;
- Cramer, Jeffrey W.;
- Audia, James E.;
- Nissen, Jeffrey S.;
- Bales, Kelly R.;
- Paul, Steven M.;
- DeMattos, Ronald B.;
- Holtzman, David M.
Publication type:
Article
Insufficient evidence for an association between iatrogenic Alzheimer's disease and cadaveric pituitary‐derived growth hormone.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 10, p. 7399, doi. 10.1002/alz.14127
By:
- Nath, Avi;
- Holtzman, David M.;
- Miller, Bruce L.;
- Grinberg, Lea T.;
- Leschek, Ellen Werber
Publication type:
Article
Clinical validation of the PrecivityAD2 blood test: A mass spectrometry‐based test with algorithm combining %p‐tau217 and Aβ42/40 ratio to identify presence of brain amyloid.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 5, p. 3179, doi. 10.1002/alz.13764
By:
- Meyer, Matthew R.;
- Kirmess, Kristopher M.;
- Eastwood, Stephanie;
- Wente‐Roth, Traci L.;
- Irvin, Faith;
- Holubasch, Mary S.;
- Venkatesh, Venky;
- Fogelman, Ilana;
- Monane, Mark;
- Hanna, Lucy;
- Rabinovici, Gil D.;
- Siegel, Barry A.;
- Whitmer, Rachel A.;
- Apgar, Charles;
- Bateman, Randall J.;
- Holtzman, David M.;
- Irizarry, Michael;
- Verbel, David;
- Sachdev, Pallavi;
- Ito, Satoshi
Publication type:
Article
Mapping sleep's oscillatory events as a biomarker of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 1, p. 301, doi. 10.1002/alz.13420
By:
- Pulver, Rachelle L.;
- Kronberg, Eugene;
- Medenblik, Lindsey M.;
- Kheyfets, Vitaly O.;
- Ramos, Alberto R.;
- Holtzman, David M.;
- Morris, John C.;
- Toedebusch, Cristina D.;
- Sillau, Stefan H;
- Bettcher, Brianne M.;
- Lucey, Brendan P.;
- McConnell, Brice V.
Publication type:
Article
A machine learning examination of the utility of CSF, neuroimaging, and plasma biomarkers in late onset Alzheimer Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.070918
By:
- Meeker, Karin L.;
- Luckett, Patrick H.;
- Barthélemy, Nicolas R.;
- Hassenstab, Jason J.;
- Xiong, Chengjie;
- Cruchaga, Carlos;
- Benzinger, Tammie L.S.;
- Schindler, Suzanne E.;
- Bateman, Randall J.;
- Holtzman, David M.;
- Morris, John C;
- Gordon, Brian A.;
- Ances, Beau
Publication type:
Article
Evaluating brain age as a marker of autosomal dominant Alzheimer disease progression.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.070790
By:
- Millar, Peter R;
- Gordon, Brian A.;
- Benzinger, Tammie L.S.;
- Cruchaga, Carlos;
- Fagan, Anne M.;
- Goate, Alison;
- Hassenstab, Jason J.;
- Holtzman, David M.;
- Llibre‐Guerra, Jorge J;
- Morris, John C;
- Perrin, Richard J.;
- Supnet, Charlene B;
- Xiong, Chengjie;
- Bateman, Randall J.;
- Ances, Beau;
- McDade, Eric
Publication type:
Article
The gut microbiome as an early biomarker of preclinical Alzheimer disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078811
By:
- Ances, Beau;
- Ferreiro, Aura L.;
- Choi, JooHee;
- Ryou, Jian;
- Newcomer, Erin;
- Stark, Susan L.;
- Benzinger, Tammie L.S.;
- Holtzman, David M.;
- Fagan, Anne M.;
- Schindler, Suzanne E.;
- Cruchaga, Carlos;
- Butt, Omar Hameed;
- Morris, John C;
- Tarr, Philip;
- Dantas, Gautam
Publication type:
Article
Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer's.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.075367
By:
- Salvadó, Gemma;
- Horie, Kanta;
- Barthélemy, Nicolas R.;
- Vogel, Jacob W;
- Binette, Alexa Pichet;
- Chen, Charles D.;
- Gordon, Brian A.;
- Benzinger, Tammie L.S.;
- Holtzman, David M.;
- Morris, John C;
- Palmqvist, Sebastian;
- Stomrud, Erik;
- Janelidze, Shorena;
- Ossenkoppele, Rik;
- Schindler, Suzanne E.;
- Bateman, Randall J.;
- Hansson, Oskar
Publication type:
Article
Phospholipase D3 drives microglial response to amyloid pathology in Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076884
By:
- Rosene, Matthew J;
- Danhash, Emma;
- You, Shih‐Feng;
- Iyer, Abhirami Kannan;
- Hsu, Simon;
- de Sa Lopes, Mariana Acquarone;
- Brase, Logan;
- Verbeck, Anthony;
- Martinez, Rita;
- Wallace, Clare E;
- Li, Zeran;
- Yan, Ping;
- Drager, Nina;
- Sattler, Sydney M;
- Mahan, Thomas E;
- Macauley, Shannon L;
- Holtzman, David M.;
- Benitez, Bruno A.;
- Kampmann, Martin;
- Cruchaga, Carlos
Publication type:
Article
Xenon gas (Xe) treatment to restore microglial functions in Alzheimer's disease (AD).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076467
By:
- Brandao, Wesley N;
- Yin, Zhuoran;
- Kleemann, Kilian;
- Zhang, Xiaoming;
- Rosenzweig, Neta;
- Jain, Nimansha;
- Jones, Mathew Blurton;
- Holtzman, David M.;
- Ilin, Ilya;
- Weiner, Howard L;
- Butovsky, Oleg
Publication type:
Article
Modeling neuropathology of Alzheimer's disease in aged patient‐derived neurons through 3D direct neuronal reprogramming.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.074488
By:
- Sun, Zhao;
- Chen, Shawei;
- Cates, Kitra;
- Kwon, Ji‐Sun;
- Sviben, Sanja;
- Ren, Yudong;
- Lv, Xinguo;
- Karahan, Hande;
- Sato, Chihiro;
- Houlden, Henry;
- Karch, Celeste M.;
- Bateman, Randall J.;
- Mennerick, Steven;
- Kim, Jungsu;
- Diamond, Marc;
- Tanzi, Rudolph E.;
- Holtzman, David M.;
- Yoo, Andrew S
Publication type:
Article
Microglia‐mediated T cell Infiltration Drives Neurodegeneration in Tauopathy.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.070849
By:
- Chen, Xiaoying;
- Firulyova, Maria;
- Manis, Melissa;
- Herz, Jasmin;
- Smirnov, Igor;
- Aladyeva, Ekaterina;
- Wang, Chanung;
- Bao, Xin;
- Finn, Mary Beth;
- Hu, Hao;
- Shchukina, Irina;
- Kim, Min Woo;
- Yuede, Carla M;
- Kipnis, Jonathan;
- Artyomov, Maxim N;
- Ulrich, Jason D;
- Holtzman, David M.
Publication type:
Article
Novel CSF tau biomarkers can be used for disease staging of sporadic Alzheimer's.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081678
By:
- Salvadó, Gemma;
- Horie, Kanta;
- Barthélemy, Nicolas R.;
- Vogel, Jacob W;
- Binette, Alexa Pichet;
- Chen, Charles D.;
- Gordon, Brian A.;
- Benzinger, Tammie L.S.;
- Holtzman, David M.;
- Morris, John C;
- Palmqvist, Sebastian;
- Stomrud, Erik;
- Janelidze, Shorena;
- Ossenkoppele, Rik;
- Schindler, Suzanne E.;
- Bateman, Randall J.;
- Hansson, Oskar
Publication type:
Article
Evaluating brain age as a marker of autosomal dominant Alzheimer disease progression.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081573
By:
- Millar, Peter R;
- Gordon, Brian A.;
- Benzinger, Tammie L.S.;
- Cruchaga, Carlos;
- Fagan, Anne M.;
- Goate, Alison;
- Hassenstab, Jason J.;
- Holtzman, David M.;
- Llibre‐Guerra, Jorge J;
- Morris, John C;
- Perrin, Richard J.;
- Supnet, Charlene B;
- Xiong, Chengjie;
- Bateman, Randall J.;
- Ances, Beau;
- McDade, Eric
Publication type:
Article
Using Alzheimer's disease blood tests to accelerate clinical trial enrollment.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 4, p. 1175, doi. 10.1002/alz.12754
By:
- Schindler, Suzanne E.;
- Li, Yan;
- Li, Melody;
- Despotis, Alyssa;
- Park, Ethan;
- Vittert, Liberty;
- Hamilton, Barton H.;
- Womack, Kyle B.;
- Saef, Benjamin;
- Holtzman, David M.;
- Morris, John C.;
- Bateman, Randall J.;
- Gupta, Mahendra R.
Publication type:
Article
Plasma ratio of phospho‐ to non‐phospho‐tau at threonine 217 identifies brain amyloid burden as measured by quantitative amyloid PET in the PARIS sub‐study of IDEAS.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.068767
By:
- Meyer, Matthew R.;
- Kirmess, Kristopher M.;
- Wente‐Roth, Traci L.;
- Irvin, Faith;
- Holubasch, Mary S.;
- Verghese, Philip B.;
- Monane, Mark;
- Bateman, Randall J.;
- Holtzman, David M.;
- Venkatesh, Venky;
- Fogelman, Ilana;
- Yarasheski, Kevin E.;
- Braunstein, Joel B.;
- West, Tim
Publication type:
Article
CSF tau phosphorylation at sites 217 and 205 mediate the relationship between PET amyloid and downstream AD markers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.065718
By:
- Meeker, Karin L.;
- Barthélemy, Nicolas R.;
- Gordon, Brian A.;
- McDade, Eric;
- Karch, Celeste M.;
- Fagan, Anne M.;
- Strain, Jeremy F.;
- Luckett, Patrick H;
- Benzinger, Tammie L.S.;
- Bateman, Randall J.;
- Holtzman, David M.;
- Ances, Beau M
Publication type:
Article
CSF tau phosphorylation at sites 217 and 181 are associated with preclinical and biphasic alterations in resting‐state functional connectivity in Autosomal Dominant AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.065641
By:
- Meeker, Karin L.;
- Barthélemy, Nicolas R.;
- Gordon, Brian A.;
- McDade, Eric;
- Karch, Celeste M.;
- Fagan, Anne M.;
- Strain, Jeremy F.;
- Luckett, Patrick H;
- Benzinger, Tammie L.S.;
- Bateman, Randall J.;
- Holtzman, David M.;
- Ances, Beau M
Publication type:
Article
Network dysfunction in cognitively normal APOE ε4 carriers is related to subclinical tau.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 1, p. 116, doi. 10.1002/alz.12375
By:
- Butt, Omar H.;
- Meeker, Karin L.;
- Wisch, Julie K.;
- Schindler, Suzanne E.;
- Fagan, Anne M.;
- Benzinger, Tammie L. S.;
- Cruchaga, Carlos;
- Holtzman, David M.;
- Morris, John C.;
- Ances, Beau M.
Publication type:
Article
The interaction of APOE genotype and amyloid‐β PET predicts PET but not CSF measures of tauopathy in regions of high APOE mRNA expression.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.052249
By:
- Dincer, Aylin;
- Chen, Charles D.;
- McKay, Nicole S.;
- McCullough, Austin A.;
- Flores, Shaney E.;
- Keefe, Sarah J.;
- Schultz, Stephanie A.;
- Feldman, Rebecca L.;
- Hornbeck, Russ C.;
- Cruchaga, Carlos;
- Holtzman, David M.;
- Morris, John C.;
- Benzinger, Tammie L.S.;
- Gordon, Brian A.
Publication type:
Article
Correspondence of CSF biomarkers measured by Lumipulse assays with amyloid PET.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.051085
By:
- Volluz, Katherine E.;
- Schindler, Suzanne E.;
- Henson, Rachel L.;
- Xiong, Chengjie;
- Gordon, Brian A.;
- Benzinger, Tammie L.S.;
- Holtzman, David M.;
- Morris, John C.;
- Fagan, Anne M.
Publication type:
Article
CSF and blood plasma mass spectrometry measures of Aβ, tau, and NfL species and longitudinal relationship to preclinical and clinical staging of amyloid and tau aggregation and clinical stage of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.050711
By:
- Bateman, Randall J.;
- Barthelemy, Nicolas R.;
- Benzinger, Tammie L.S.;
- Bollinger, James G.;
- Fagan, Anne M.;
- Gordon, Brian A.;
- Hansson, Oskar;
- Holtzman, David M.;
- Horie, Kanta;
- Li, Melody;
- Masters, Colin L;
- Mawuenyega, Kwasi G.;
- McDade, Eric;
- Morris, John C.;
- Ovod, Vitaliy;
- Budelier, Melissa;
- He, Chloe;
- Petersen, Ronald C.;
- Mielke, Michelle M.;
- Sato, Chihiro
Publication type:
Article
25‐Hydroxycholesterol modulates tau‐mediated neurodegeneration and microglial chemotaxis and phagocytosis.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.056404
By:
- Long, Justin M;
- Tran, Ainsley;
- Serrano, Javier R.;
- Bao, Xin;
- Wang, Chao;
- Reznikov, Joseph;
- Cashikar, Anil G;
- Paul, Steven M.;
- Holtzman, David M.
Publication type:
Article
Evidence that the gut microbiota regulates progression of neurodegeneration in a mouse model of tauopathy, in a sex‐ and ApoE isoform‐dependent manner.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.049741
By:
- Seo, Dong‐oh;
- Stanley, Jack G.;
- Shi, Yang;
- Wang, Chao;
- Serrano, Javier R.;
- Bao, Xin;
- O'Donnell, David;
- Lelwala‐Guruge, Janaki;
- Griffin, Nicholas;
- Meier, Marty;
- Dodiya, Hemraj B.;
- Sisodia, Sangram S.;
- Gordon, Jeffrey I.;
- Holtzman, David M.
Publication type:
Article
Functional insights from biophysical study of TREM2 interactions with apoE and Aβ1‐42.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 475, doi. 10.1002/alz.12194
By:
- Kober, Daniel L.;
- Stuchell‐Brereton, Melissa D.;
- Kluender, Colin E.;
- Dean, Hunter B.;
- Strickland, Michael R.;
- Steinberg, Deborah F.;
- Nelson, Samantha S.;
- Baban, Berevan;
- Holtzman, David M.;
- Frieden, Carl;
- Alexander‐Brett, Jennifer;
- Roberson, Erik D.;
- Song, Yuhua;
- Brett, Tom J.
Publication type:
Article

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