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- Title
A Nonhospitable Host: Targeting Cellular Factors as an Antiviral Strategy for Respiratory Viruses.
- Authors
Amarelle, Luciano; Lecuona, Emilia
- Abstract
The article discusses cardiac glycosides digoxin and digitoxin produced robust inhibition of Respiratory syncytial virus (RSV) replication in vitro. It mentions that inhibitory effect of cardiac glycosides on RSV replication was due to decreased Na, KATPase activity and consequent changes in the intracellular concentrations of Na ions and K ions.
- Subjects
RESPIRATORY syncytial virus infections; VIRAL replication; IN vitro studies; CARDIAC glycosides; DIGOXIN
- Publication
American Journal of Respiratory Cell & Molecular Biology, 2018, Vol 59, Issue 6, p666
- ISSN
1044-1549
- Publication type
Article
- DOI
10.1165/rcmb.2018-0268ed