We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Genomic imprinting status of IGF-II and H19 in placentas of fetal growth restriction patients.
- Authors
Ying Wang; Jing Li Fu; Wei Wei Song; Li Li Wang
- Abstract
The article presents a study which examines loss of imprinting (LOI) of insulin-like growth factor-II (IGF-II) gene and its reciprocal imprinted gene H19 in placentas of fetal growth restriction (FGR). The study involves extraction of genomic DNA using an isolation kit, wherein the overall RNA was removed from placenta tissue. Results of the study reveal the exclusive presence of IGF-II expression in an allele through the use of ApaI restriction site polymorphism.
- Subjects
SOMATOMEDIN; GENOMIC imprinting; FETAL development; GENETIC polymorphisms; DNA; PLACENTA
- Publication
Journal of Genetics, 2010, Vol 89, Issue 2, p213
- ISSN
0022-1333
- Publication type
Article
- DOI
10.1007/s12041-010-0027-9