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- Title
Effect of suplatast tosilate, an antiallergic selective Th2 cytokine inhibitor, on acute eosinophilic myocarditis: a case report.
- Authors
Umemoto, Seiji; Itagaki, Kazuo; Kimura, Masahiro; Itoh, Shinichi; Tanaka, Masakazu; Haraguchi, Masahiko; Matsuzaki, Masunori
- Abstract
We encountered a 44-year-old woman with acute eosinophilic myocarditis that showed positive immunostaining for interleukin-4 in the area of marked infiltration of eosinophils into the myocardium. When prednisolone alone proved ineffective, supplementary treatment with suplatast tosilate, an antiallergic selective Th2 cytokine inhibitor, improved the patient's inflammation, reduced the level of cardiac enzymes, and allowed for a reduction in corticosteroid dosage without any adverse effects.
- Subjects
MYOCARDITIS; INTERLEUKIN-4; CARDIOMYOPATHIES; ADRENOCORTICAL hormones; ENZYMES; ANTIALLERGIC agents
- Publication
Heart & Vessels, 2003, Vol 18, Issue 2, p100
- ISSN
0910-8327
- Publication type
Article
- DOI
10.1007/s10380-002-0689-2