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- Title
Feasibility and reproducibility of biventricular volumetric assessment of cardiac function during exercise using real-time radial k-t SENSE magnetic resonance imaging.
- Authors
Lurz P; Muthurangu V; Schievano S; Nordmeyer J; Bonhoeffer P; Taylor AM; Hansen MS; Lurz, Philipp; Muthurangu, Vivek; Schievano, Silvia; Nordmeyer, Johannes; Bonhoeffer, Philipp; Taylor, Andrew M; Hansen, Michael S
- Abstract
<bold>Purpose: </bold>To assess the feasibility and reproducibility of real-time radial k-t sensitivity encoding (SENSE) magnetic resonance imaging (MRI) for biventricular volumetric assessment during exercise.<bold>Materials and Methods: </bold>In all, 12 healthy young adults underwent MRI at rest and during supine exercise at three different workload intensities. Biventricular volumes and function were assessed with 1) a radial k-t SENSE real-time sequence and 2) a scanner vendor supplied (standard) real-time sequence. Global image quality, motion fidelity, and agreement in right ventricular (RV) and left ventricular (LV) stroke volume (SV) as a surrogate measure for accuracy were assessed. Exercise MR was repeated within 1 month for assessment of reproducibility.<bold>Results: </bold>Imaging scores were superior for radial real-time k-t SENSE images (P < 0.001). Agreement in RV and LV SV during exercise was better with radial k-t real-time (SD of difference +/-3.43 vs. +/-8.97 mL; P < 0.001). Agreement in cardiac output (CO) in the same subject at two different imaging sessions was better for radial k-t SENSE. This was significant for the CO calculated for the RV (SD of difference +/-0.6 vs. +/-0.95 L/min; P = 0.01) and LV (+/-0.45 vs. +/-0.92 L/min; P < 0.001).<bold>Conclusion: </bold>Radial k-t SENSE real-time imaging represents a feasible and reproducible imaging technique for biventricular assessment during exercise.
- Publication
Journal of Magnetic Resonance Imaging, 2009, Vol 29, Issue 5, p1062
- ISSN
1053-1807
- Publication type
journal article
- DOI
10.1002/jmri.21762