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- Title
Regioisomers Salviprolin A and B, Unprecedented Rosmarinic Acid Conjugated Dinorditerpenoids from Salvia przewalskii Maxim.
- Authors
Su, Xiangdong; Wu, Yichuang; Wu, Meifang; Lu, Jielang; Jia, Shujie; He, Xin; Liu, Shuna; Zhou, Yuyang; Xing, Hui; Xue, Yongbo
- Abstract
Salvia przewalskii Maxim is a perennial plant from the genus Salvia (family Lamiaceae). The roots of S. przewalskii were long used as a traditional herb to treat blood circulation related illnesses in China. As part of our continuing interest in polycyclic natural products from medicinal plants, two unprecedented adducts comprised of a dinor-diterpenoid and a 9′-nor-rosmarinic acid derivative, linked by a 1,4-benzodioxane motif (1 and 2), were isolated from the roots of S. przewalskii. Their structures were established by extensive spectroscopic approaches including 1D, 2D NMR, and HRFABMS. Their cytotoxic activities against five human tumor cell lines were evaluated.
- Subjects
CHINA; SALVIA miltiorrhiza; SALVIA; MEDICINAL plants; BLOOD circulation; NATURAL products; LAMIACEAE; CELL lines
- Publication
Molecules, 2021, Vol 26, Issue 22, p6955
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules26226955