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- Title
Ljungan virus is endemic in rodents in the UK.
- Authors
Salisbury, Anne-Marie; Begon, Michael; Dove, Winifred; Niklasson, Bo; Stewart, James
- Abstract
Ljungan virus is a recently identified member of the family Picornaviridae that was isolated from bank voles in Sweden. It has been shown to cause type 1 diabetes-like symptoms and myocarditis in bank voles ( Myodes glareolus), and it has been suggested that it has zoonotic potential. Here, we show for the first time that Ljungan virus is prevalent (20-27 % positive by PCR) in four species of UK rodent ( Myodes glareolus [bank vole], Apodemus sylvaticus [wood mouse], Microtus agrestis [field vole] and Mus musculus [house mouse]). Sequence analysis showed that Ljungan virus of genotypes 1 and 2 were present, although genotype 1 was more prevalent and more frequently associated with brain tissue. This study highlights the prevalence of Ljungan virus in the UK and the need for confirmation of its zoonotic potential.
- Subjects
PICORNAVIRUSES; ZOONOSES; SYMPTOMS; GENOTYPE-environment interaction; CLETHRIONOMYS glareolus; DISEASE prevalence
- Publication
Archives of Virology, 2014, Vol 159, Issue 3, p547
- ISSN
0304-8608
- Publication type
Report
- DOI
10.1007/s00705-013-1731-6