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- Title
Optic Nerve Sonography to Monitor Treatment Efficacy in Idiopathic Intracranial Hypertension: A Case Report.
- Authors
Lochner, Piergiorgio; Nardone, Raffaele; Tezzon, Frediano; Coppo, Lorenzo; Brigo, Francesco
- Abstract
ABSTRACT OBJECTIVES To report values of optic nerve sheath diameter (ONSD) and optic disc elevation (ODE) obtained with optic nerve sonography (US) in the diagnosis and monitoring of treatment efficacy in an adult with idiopathic intracranial hypertension (IIH). METHODS Serial measurements of the ONSD and ODE using B mode US were performed in a 45-years-old woman with IIH before and during after treatment with acetazolamide and diet. RESULTS At first evaluation US showed a significantly enlarged ONSD (.68 cm right; .66 cm left side) and the presence of increased ODE (.1 cm right; .15 cm left side). Post-punctural assessments showed a bilateral decrease of ONSD (.58 cm right; .58 cm left side), without changes in ODE values. After 12 months of treatment with acetazolamide and diet ODE completely normalized (0 cm on both sides). ODE values correlated directly with ONSD, and both ODE and ONSD values correlated directly with BMI. Correlations were statistically significant. ONSD changes occurred rapidly after the lumbar puncture, whereas the papilloedema required longer to reduce. CONCLUSIONS US of ONSD and ODE was useful to support the diagnosis of IIH and to monitor the efficacy of diet and pharmacological treatment. Further studies are required to evaluate whether this promising technique may be considered a reliable and accurate method to longitudinally evaluate patients with increased ICP secondary to IIH.
- Subjects
OPTIC nerve diseases; OPTIC disc; ULTRASONIC imaging; INTRACRANIAL hypertension; ACETAZOLAMIDE; THERAPEUTICS
- Publication
Journal of Neuroimaging, 2013, Vol 23, Issue 4, p533
- ISSN
1051-2284
- Publication type
Article
- DOI
10.1111/jon.12005