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- Title
Foldamers containing γ-amino acid residues or their analogues: structural features and applications.
- Authors
Bouillère, Francelin; Thétiot-Laurent, Sophie; Kouklovsky, Cyrille; Alezra, Valérie
- Abstract
Over the past 20 years, the field of foldamers has rapidly increased. Many β-peptides have already been described and shown interesting properties. γ-Peptides have more recently emerged but seem to be very interesting as well. In this review, we will cover every peptidomimetic oligomer that contains a γ-amino acid or an analogue and presents a structural feature. It includes γ-peptides but also hybrid α-γ peptides, β-γ peptides and analogues such as oligoureas or aminoxy acids. We will present the biological properties of these oligomers.
- Subjects
MOLECULAR structure; AMINO acids; PEPTIDES; OLIGOMERS; ORGANIC compounds; BIOMOLECULES
- Publication
Amino Acids, 2011, Vol 41, Issue 3, p687
- ISSN
0939-4451
- Publication type
Article
- DOI
10.1007/s00726-011-0893-3