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- Title
Wood dust exposure and the association with lung cancer risk.
- Authors
Carlos H. Barcenas; George L. Delclos; Randa El-Zein; Guillermo Tortolero-Luna; Lawrence W. Whitehead; Margaret R. Spitz
- Abstract
Wood dust was designated as a human carcinogen based on increased sinus and nasal cancer rates among exposed workers. However, data on an association with lung cancer have been inconclusive.Self-reported wood dust exposure was compared between 1,368 lung cancer patients and 1,192 cancer-free adults, in a lung cancer case-control study. Epidemiological information was collected through a detailed personal interview.Using several definitions of wood dust exposure we consistently observed statistically significant elevated adjusted risk estimates; for example, the adjusted odds ratio (OR) for combined wood dust related occupations and industries was 3.15 (95% confidence intervals (CI) 1.456.86) and for an overall summary exposure measure it was 1.60 (95% CI 1.192.14). The association was maintained when stratified by histopathological type. Among those exposed to cigarette smoke and wood dust, 21% of the cases were attributable to biologic interaction.Wood dust exposure is a potential risk factor for lung cancer. Am. J. Ind. Med. 47:349357, 2005. 2005 Wiley-Liss, Inc.
- Subjects
CANCER patients; HAZARDOUS substances; OCCUPATIONS; INDUSTRIAL toxicology
- Publication
American Journal of Industrial Medicine, 2005, Vol 47, Issue 4, p349
- ISSN
0271-3586
- Publication type
Article