We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Applying metabolomics to veterinary pharmacology and therapeutics.
- Authors
Rivera‐Velez, Sol M.; Navas, Jinna; Villarino, Nicolas F.
- Abstract
Metabolomics is the large‐scale study of low‐molecular‐weight substances in a biological system in a given physiological state at a given time point. Metabolomics can be applied to identify predictors of inter‐individual variability in drug response, provide clinicians with data useful for decision‐making processes in drug selection, and inform about the pharmacokinetics and pharmacodynamics of a drug. It is, therefore, an exceptional approach for gaining new understanding effects in the field of comparative veterinary pharmacology. However, the incorporation of metabolomics into veterinary pharmacology and toxicology is not yet widespread, and this is probably, at least in part, a result of its highly multidisciplinary nature. This article reviews the potential applications of metabolomics in veterinary pharmacology and therapeutics. It integrates key concepts for designing metabolomics studies and analyzing and interpreting metabolomics data, providing solid foundations for applying metabolomics to the study of drugs in all veterinary species.
- Subjects
VETERINARY pharmacology; VETERINARY therapeutics; METABOLOMICS; MEDICAL personnel; BIOLOGICAL systems; VETERINARY drugs
- Publication
Journal of Veterinary Pharmacology & Therapeutics, 2021, Vol 44, Issue 6, p855
- ISSN
0140-7783
- Publication type
Article
- DOI
10.1111/jvp.12961