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- Title
Spermatogenic ability is different among males in different Y chromosome lineage.
- Authors
Kuroki, Yoko; Iwamoto, Teruaki; Lee, Juwon; Yoshiike, Miki; Nozawa, Shiari; Nishida, Takayasu; Ewis, Ashraf A.; Nakamura, Hideki; Toda, Tatsushi; Tokunaga, K.; Kotliarova, Svetlana E.; Kondoh, Nobuyuki; Koh, Eitetsu; Namiki, Mikio; Shinka, Toshikatsu; Nakahori, Y.
- Abstract
Abstract It is a controversial question whether sperm concentrations in humans are changing. Several researchers have reported on environmental factors affecting sperm quality, but the influence of genetic factors is still not fully understood. In this study, we examined the relationship between Y chromosome haplotypes and sperm concentration in fertile males. In addition, we determined the haplotypes of azoospermic patients. The results show that the mean sperm concentration correlates with Y chromosome type. Moreover, the occurrence of azoospermia is related to one particular Y chromosome lineage. Thus, males with a certain haplotype are at a disadvantage for fathering children. The difference of spermatogenic ability among men is important not only in pursuing male competition as in the past but also as relates to the future of modern human males.
- Subjects
HUMAN beings; SPERMATOZOA; Y chromosome; GENETICS of spermatogenesis
- Publication
Journal of Human Genetics, 1999, Vol 44, Issue 5, p289
- ISSN
1434-5161
- Publication type
Article
- DOI
10.1007/s100380050162