We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Integrating Host Genomics with Surveillance for Invasive Bacterial Diseases.
- Authors
Crawford, Dana C.; Zimmer, Shanta M.; Morin, Craig A.; Messonnier, Nancy E.; Lynfield, Ruth; Qian Yi; Shephard, Cynthia; Wong, Michelle; Rieder, Mark J.; Livingston, Robert J.; Nickerson, Deborah A.; Whitney, Cynthia G.; Lingappa, Jairam
- Abstract
We tested the feasibility of linking Active Bacterial Core surveillance, a prospective, population-based surveillance system for invasive bacterial disease, to a newborn dried blood spot (nDBS) repository. Using nDBS specimens, we resequenced CD46, putative host gene receptor for Neisseria meningitidis, and identified variants associated with susceptibility to this disease.
- Subjects
BACTERIAL diseases in children; INFANT diseases; GENOMICS; INFANT health services; NEISSERIA meningitidis; BLOOD testing
- Publication
Emerging Infectious Diseases, 2008, Vol 14, Issue 7, p1138
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid1407.071287