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- Title
Citrullus colocynthis as a bioavailable source of β-sitosterol, antihyperlipidemic effect of oil in rabbits.
- Authors
Talabani, Namama S.; Tofiq, Diary I.
- Abstract
A phytochemical study on the seed and kernel of citrullus colocynthis has been carried out in the present paper. The results revealed the presence of β-sitosterol in the kernel and seed in different percentages (seed contains 16.92%,and the kernel contains 6.62%). The lipid lowering active compound (β-sitosterol) has been detected by using TLC, IR, UV and H1-NMR. The present study was designed to reveal the hypocholesterolemic effect of b-sitosterol on the serum total cholesterol and triglyceride in rabbits. A significant drop in serum total cholesterol and triglyceride was observed at 120 hours after first administration. These results support the suggestion of citrullus colocynthis oil as a treatment for hyperlipidemia.
- Subjects
BOTANICAL chemistry; CITRULLUS; SEED research; PHYTOSTEROLS; CHOLESTEROL; TRIGLYCERIDES; LABORATORY rabbits
- Publication
Middle East Journal of Internal Medicine, 2013, Vol 6, Issue 1, p12
- ISSN
1837-9052
- Publication type
Article
- DOI
10.5742/mejim.2013.61196