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- Title
Copper(II)-Catalyzed Direct Azidation of N-Acylated 8-Aminoquinolines by Remote C−H Activation.
- Authors
Dou, Yandong; Xie, ZhENda; Sun, Zongguo; Fang, Hongli; ShEN, Chao; Zhang, PENgfei; Zhu, Qing
- Abstract
A simple and efficient copper(II)-catalyzed C5 azidation of N-acylated 8-aminoquinolines by remote C−H activation was developed. On the basis of this reaction, a series of new C5-azidated 8-amidequinolines were synthesized in moderate to good yields.
- Subjects
COPPER catalysts; AZIDATION; AZIDES; FUNCTIONAL groups; BIOACTIVE compounds; RING formation (Chemistry)
- Publication
ChemCatChem, 2016, Vol 8, Issue 23, p3570
- ISSN
1867-3880
- Publication type
Article
- DOI
10.1002/cctc.201600874