We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Visible‐Light‐Induced Oxidative α‐Alkylation of Glycine Derivatives with Ethers under Metal‐Free Conditions.
- Authors
Song, Yang; Zhang, Hao; Guo, Jiabao; Shao, Yifei; Ding, Yuzhou; Zhu, Li; Yao, Xiaoquan
- Abstract
In this work, a visible‐light‐induced oxidative α‐alkylation of glycine derivatives with ethers has been developed in the presence of catalytic Eosin Y. Under the blue light of a 3 W LED, a range of α‐etherized glycine derivatives, including α‐amino esters, α‐amino ketones and α‐amino amides, were achieved with good to excellent yields and functional group tolerance with tert‐butyl hydroperoxide (TBHP) as oxidant at ambient temperature. The operationally easy procedure provides an economical, metal‐free, and mild alternative for the synthesis of the α‐etherized glycine derivatives.
- Subjects
ETHER derivatives; GLYCINE; BLUE light; FUNCTIONAL groups; AMIDES
- Publication
European Journal of Organic Chemistry, 2021, Vol 2021, Issue 44, p5914
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.202101242