We found a match
Your institution may have rights to this item. Sign in to continue.
- Title
Polycarbonate microspheres containing tumor necrosis factor-α genes and magnetic powder as potential cancer therapeutics.
- Authors
Hu, Bin; Yan, Guo-Ping; Zhuo, Ren-Xi; Wu, Yuan; Fan, Chang-Lie
- Abstract
The article discusses a study which involved the development of anticancer magnetic polymer microspheres with tumor necrosis factor-α (TNF-α) genes. The water-in-oil-in-water solvent evaporation technique was used to produce the polymer microspheres with results showing a sustained release rate of the TNF-α genes for up to 60 hours. A new method of drug release for liver carcinoma treatment shown by high antitumor activity and inhibitory rate of the microspheres is proposed.
- Subjects
POLYMERS; POLYCARBONATES; TUMOR necrosis factors; CANCER treatment; LIVER cancer
- Publication
Journal of Applied Polymer Science, 2008, Vol 107, Issue 5, p3343
- ISSN
0021-8995
- Publication type
Article
- DOI
10.1002/app.27544