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Brain Imaging and Blood Biomarker Abnormalities in Children With Autosomal Dominant Alzheimer Disease.
Published in:
JAMA Dermatology, 2015, v. 151, n. 8, p. 912, doi. 10.1001/jamaneurol.2015.1099
By:
- Quiroz, Yakeel T.;
- Schultz, Aaron P.;
- Chen, Kewei;
- Protas, Hillary D.;
- Brickhouse, Michael;
- Fleisher, Adam S.;
- Langbaum, Jessica B.;
- Thiyyagura, Pradeep;
- Fagan, Anne M.;
- Shah, Aarti R.;
- Muniz, Martha;
- Arboleda-Velasquez, Joseph F.;
- Munoz, Claudia;
- Garcia, Gloria;
- Acosta-Baena, Natalia;
- Giraldo, Margarita;
- Tirado, Victoria;
- Ramírez, Dora L.;
- Tariot, Pierre N.;
- Dickerson, Bradford C.
Publication type:
Article
Plasma VEGFA and PGF impact longitudinal tau and cognition in preclinical Alzheimer's disease.
Published in:
Brain: A Journal of Neurology, 2024, v. 147, n. 6, p. 2158, doi. 10.1093/brain/awae034
By:
- Yang, Hyun-Sik;
- Yau, Wai-Ying Wendy;
- Carlyle, Becky C;
- Trombetta, Bianca A;
- Zhang, Can;
- Shirzadi, Zahra;
- Schultz, Aaron P;
- Pruzin, Jeremy J;
- Fitzpatrick, Colleen D;
- Kirn, Dylan R;
- Rabin, Jennifer S;
- Buckley, Rachel F;
- Hohman, Timothy J;
- Rentz, Dorene M;
- Tanzi, Rudolph E;
- Johnson, Keith A;
- Sperling, Reisa A;
- Arnold, Steven E;
- Chhatwal, Jasmeer P
Publication type:
Article
Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing.
Published in:
2018
By:
- Chhatwal, Jasmeer P.;
- Schultz, Aaron P.;
- Johnson, Keith A.;
- Hedden, Trey;
- Jaimes, Sehily;
- Benzinger, Tammie L. S.;
- Jack Jr, Clifford;
- Ances, Beau M.;
- Ringman, John M.;
- Marcus, Daniel S.;
- Ghetti, Bernardino;
- Farlow, Martin R.;
- Danek, Adrian;
- Levin, Johannes;
- Yakushev, Igor;
- Laske, Christoph;
- Koeppe, Robert A.;
- Galasko, Douglas R.;
- Chengjie Xiong;
- Masters, Colin L.
Publication type:
journal article
Amyloid-β deposition in mild cognitive impairment is associated with increased hippocampal activity, atrophy and clinical progression.
Published in:
Brain: A Journal of Neurology, 2015, v. 138, n. 4, p. 1023, doi. 10.1093/brain/awv007
By:
- Huijbers, Willem;
- Mormino, Elizabeth C.;
- Schultz, Aaron P.;
- Wigman, Sarah;
- Ward, Andrew M.;
- Larvie, Mykol;
- Amariglio, Rebecca E.;
- Marshall, Gad A.;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Sperling, Reisa A.
Publication type:
Article
Spatial extent as a sensitive amyloid‐PET metric in preclinical Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 8, p. 5434, doi. 10.1002/alz.14036
By:
- Farrell, Michelle E.;
- Thibault, Emma G.;
- Becker, J. Alex;
- Price, Julie C.;
- Healy, Brian C.;
- Hanseeuw, Bernard J.;
- Buckley, Rachel F.;
- Jacobs, Heidi I. L.;
- Schultz, Aaron P.;
- Chen, Charles D.;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Atrophy links lower novelty‐related locus coeruleus connectivity to cognitive decline in preclinical AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 6, p. 3958, doi. 10.1002/alz.13839
By:
- Schneider, Christoph;
- Prokopiou, Prokopis C.;
- Papp, Kathryn V.;
- Engels‐Domínguez, Nina;
- Hsieh, Stephanie;
- Juneau, Truley A.;
- Schultz, Aaron P.;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I. L.
Publication type:
Article
Spatial Extent as a more sensitive amyloid biomarker for early stages of Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083164
By:
- Farrell, Michelle E.;
- Thibault, Emma G.;
- Becker, Alex;
- Price, Julie C;
- Schultz, Aaron P.;
- Properzi, Michael J;
- Buckley, Rachel F.;
- Jacobs, Heidi I.L.;
- Hanseeuw, Bernard J;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Defining and characterizing neocortical tau resistance in preclinical Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.083125
By:
- Properzi, Michael J;
- Townsend, Diana;
- Klinger, Hannah M;
- Boyle, Rory;
- Coughlan, Gillian T;
- Hanseeuw, Bernard J;
- Amariglio, Rebecca E.;
- Rentz, Dorene M.;
- Jacobs, Heidi I.L.;
- Price, Julie C;
- Chhatwal, Jasmeer P.;
- Schultz, Aaron P.;
- Hohman, Timothy J.;
- Donohue, Michael C.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Buckley, Rachel F.
Publication type:
Article
Reduced slow‐wave sleep is associated with greater tau accumulation and reduced cortical thickness in the temporal lobe.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082749
By:
- Stankeviciute, Laura;
- Chhatwal, Jasmeer P.;
- Levin, Raina;
- Pinilla, Valentina;
- Schultz, Aaron P.;
- Redline, Susan;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Kozhemiako, Nataliia;
- Purcell, Shaun;
- Djonlagic, Ina
Publication type:
Article
High VEGF‐A and low PlGF in plasma are associated with reduced longitudinal tau PET burden and slower cognitive decline in preclinical Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082453
By:
- Yau, Wai‐Ying Wendy;
- Yang, Hyun‐Sik;
- Carlyle, Becky C.;
- Trombetta, Bianca A.;
- Zhang, Can;
- Schultz, Aaron P.;
- Pruzin, Jeremy J.;
- Fitzpatrick, Colleen D;
- Kirn, Dylan;
- Rabin, Jennifer S.;
- Buckley, Rachel F.;
- Hohman, Timothy J.;
- Rentz, Dorene M.;
- Tanzi, Rudolph E.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Arnold, Steven E.;
- Chhatwal, Jasmeer P.
Publication type:
Article
Functional variations in gamma‐secretase processing of APP are critical determinants of the clinical, biomarker, and cognitive progression of autosomal dominant Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082318
By:
- Schultz, Stephanie A.;
- Liu, Lei;
- Schultz, Aaron P.;
- Fitzpatrick, Colleen D;
- Levin, Raina;
- Bellier, Jean‐Pierre;
- Shirzadi, Zahra;
- Joseph‐Mathurin, Nelly;
- Chen, Charles D.;
- Benzinger, Tammie L.S.;
- Day, Gregory S.;
- Farlow, Martin R.;
- Hassenstab, Jason J.;
- Jack, Clifford R.;
- Jucker, Mathias;
- Lee, Jae‐Hong;
- Levin, Johannes;
- Perrin, Richard J.;
- Schofield, Peter W.;
- Karch, Celeste M.
Publication type:
Article
Estimating a clinically normal individual's position along a preclinical Alzheimer's disease continuum using cognitive and amyloid trajectories.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078401
By:
- Townsend, Diana;
- Properzi, Michael J;
- Betthauser, Tobey J;
- Klinger, Hannah M;
- Boyle, Rory;
- Coughlan, Gillian T;
- Hanseeuw, Bernard J;
- Yang, Hyun‐Sik;
- Amariglio, Rebecca E.;
- Farrell, Michelle E.;
- Jacobs, Heidi I.L.;
- Shirzadi, Zahra;
- Yau, Wai‐Ying Wendy;
- Price, Julie C;
- Chhatwal, Jasmeer P.;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Schultz, Aaron P.;
- Buckley, Rachel F.
Publication type:
Article
Braak‐stage II atrophy links lower locus coeruleus – medial temporal lobe connectivity to cognitive decline in preclinical AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079240
By:
- Schneider, Christoph;
- Prokopiou, Prokopis C.;
- Papp, Kathryn V.;
- Hsieh, Stephanie;
- Schultz, Aaron P.;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
Systemic vascular risk, white matter injury, and relative cerebral blood flow independently contribute to cognitive decline beyond amyloid and tau burden.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077904
By:
- Shirzadi, Zahra;
- Yau, Wai‐Ying Wendy;
- Boyle, Rory;
- Properzi, Michael J;
- Buckley, Rachel F.;
- Yang, Hyun‐Sik;
- Scanlon, Catherine E;
- Hsieh, Stephanie;
- Amariglio, Rebecca E.;
- Papp, Kathryn V.;
- Rentz, Dorene M.;
- Price, Julie C;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Chhatwal, Jasmeer P.;
- Schultz, Aaron P.
Publication type:
Article
Left Frontoparietal Connectivity Counteracts Locus Coeruleus‐Related Attentional Decline in Preclinical Alzheimer's Disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079733
By:
- Pahl, Jennifer;
- Prokopiou, Prokopis C.;
- Bueicheku, Elisenda;
- Schultz, Aaron P.;
- Papp, Kathryn V.;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
Examining the influence of changes in amyloid burden on both contemporaneous and subsequent cognitive decline: using a latent change score approach.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078893
By:
- Klinger, Hannah M;
- Healy, Brian;
- Hanseeuw, Bernard J;
- Jones, Rich;
- Townsend, Diana;
- Properzi, Michael J;
- Farrell, Michelle E.;
- Papp, Kathryn V.;
- Chhatwal, Jasmeer P.;
- Yang, Hyun‐Sik;
- Schultz, Aaron P.;
- Amariglio, Rebecca E.;
- Jacobs, Heidi I.L.;
- Price, Julie C;
- Johnson, Keith A.;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Buckley, Rachel F.
Publication type:
Article
Functional connectivity of the frontoparietal control network is positively associated with cognition, independent of amyloid and tau burden, in the A4 study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078624
By:
- Boyle, Rory;
- Shirzadi, Zahra;
- Coughlan, Gillian T;
- Properzi, Michael J;
- Chhatwal, Jasmeer P.;
- Buckley, Rachel F.;
- Sperling, Reisa A.;
- Schultz, Aaron P.
Publication type:
Article
Sex differences in plasma p‐tau181 accumulation is associated with subsequent tau‐PET signal.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079098
By:
- Hsieh, Stephanie;
- Townsend, Diana;
- Coughlan, Gillian T;
- Boyle, Rory;
- Klinger, Hannah M;
- Seto, Mabel;
- Hanseeuw, Bernard J;
- Yang, Hyun‐Sik;
- Amariglio, Rebecca E.;
- Hassenstab, Jason J.;
- Hohman, Timothy J.;
- James, Bryan D;
- Risacher, Shannon L;
- Properzi, Michael J;
- Schultz, Aaron P.;
- Baker, Suzanne L.;
- Sperling, Reisa A.;
- Buckley, Rachel F.
Publication type:
Article
Parental history of memory impairment predicts β‐amyloid burden and positivity in a preclinical population.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078420
By:
- Seto, Mabel;
- Hohman, Timothy J.;
- Mormino, Elizabeth C.;
- Papp, Kathryn V.;
- Amariglio, Rebecca E.;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Schultz, Aaron P.;
- Sperling, Reisa A.;
- Buckley, Rachel F.;
- Yang, Hyun‐Sik
Publication type:
Article
Examining the influence of changes in amyloid burden on both contemporaneous and subsequent cognitive decline: using a latent change score approach.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081851
By:
- Klinger, Hannah M;
- Healy, Brian;
- Hanseeuw, Bernard J;
- Jones, Rich;
- Townsend, Diana;
- Properzi, Michael J;
- Farrell, Michelle E.;
- Papp, Kathryn V.;
- Chhatwal, Jasmeer P.;
- Yang, Hyun‐Sik;
- Schultz, Aaron P.;
- Amariglio, Rebecca E.;
- Jacobs, Heidi I.L.;
- Price, Julie C;
- Johnson, Keith A.;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Buckley, Rachel F.
Publication type:
Article
Functional connectivity of the frontoparietal control network is positively associated with cognition, independent of amyloid and tau burden, in the A4 study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081824
By:
- Boyle, Rory;
- Shirzadi, Zahra;
- Coughlan, Gillian T;
- Properzi, Michael J;
- Chhatwal, Jasmeer P.;
- Buckley, Rachel F.;
- Sperling, Reisa A.;
- Schultz, Aaron P.
Publication type:
Article
Parental history of memory impairment predicts β‐amyloid burden and positivity in a preclinical population.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081812
By:
- Seto, Mabel;
- Hohman, Timothy J.;
- Mormino, Elizabeth C.;
- Papp, Kathryn V.;
- Amariglio, Rebecca E.;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Schultz, Aaron P.;
- Sperling, Reisa A.;
- Buckley, Rachel F.;
- Yang, Hyun‐Sik
Publication type:
Article
Sex differences in plasma p‐tau181 accumulation is associated with subsequent tau‐PET signal.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079098
By:
- Hsieh, Stephanie;
- Townsend, Diana;
- Coughlan, Gillian T;
- Boyle, Rory;
- Klinger, Hannah M;
- Seto, Mabel;
- Hanseeuw, Bernard J;
- Yang, Hyun‐Sik;
- Amariglio, Rebecca E.;
- Hassenstab, Jason J.;
- Hohman, Timothy J.;
- James, Bryan D;
- Risacher, Shannon L;
- Properzi, Michael J;
- Schultz, Aaron P.;
- Baker, Suzanne L.;
- Sperling, Reisa A.;
- Buckley, Rachel F.
Publication type:
Article
Parental history of memory impairment predicts β‐amyloid burden and positivity in a preclinical population.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078420
By:
- Seto, Mabel;
- Hohman, Timothy J.;
- Mormino, Elizabeth C.;
- Papp, Kathryn V.;
- Amariglio, Rebecca E.;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Schultz, Aaron P.;
- Sperling, Reisa A.;
- Buckley, Rachel F.;
- Yang, Hyun‐Sik
Publication type:
Article
IC‐P‐041: LONGITUDINAL CHANGE OF FUNCTIONAL CONNECTIVITY IN PRECLINICAL AD: RESULTS FROM THE HARVARD AGING BRAIN STUDY.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 14, p. P41, doi. 10.1016/j.jalz.2018.06.2105
By:
- Schultz, Aaron P.;
- Chhatwal, Jasmeer P.;
- Hedden, Trey;
- Buckley, Rachel F.;
- Johnson, Keith A.;
- Sperling, Reisa A.
Publication type:
Article
Lower novelty‐related locus coeruleus function is associated with entorhinal tau‐mediated memory decline in older individuals.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.067706
By:
- Prokopiou, Prokopis C.;
- Engels, Nina;
- Schneider, Christoph;
- Schultz, Aaron P.;
- Sepulcre, Jorge;
- Riphagen, Joost M.;
- Koops, Elouise A.;
- Papp, Kathryn V.;
- Fakhri, Georges El;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
The relationship between everyday functioning and cerebral tau burden in cognitively normal older adults.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 7, p. 1, doi. 10.1002/alz.062840
By:
- Dubbelman, Mark A.;
- Sanchez, Justin S;
- Schultz, Aaron P.;
- Rentz, Dorene M.;
- Amariglio, Rebecca E.;
- Sikkes, Sietske A.M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Marshall, Gad A
Publication type:
Article
Longitudinal hippocampal atrophy is associated with cognitive decline independently of amyloid and tau in neocortex.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.069271
By:
- Hanseeuw, Bernard;
- Jacobs, Heidi I.L.;
- Schultz, Aaron P;
- Buckley, Rachel F.;
- Properzi, Michael J;
- Becker, Alex;
- Farrell, Michelle E.;
- Sanchez, Justin S;
- Papp, Kathryn V.;
- Yang, Hyun‐Sik;
- Chhatwal, Jasmeer P.;
- Price, Julie C;
- Fakhri, Georges El;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Optimizing early detection of beta‐amyloid accumulation with PET using spatial extent.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.068029
By:
- Farrell, Michelle E.;
- Thibault, Emma G.;
- Becker, Alex;
- Price, Julie C;
- Schultz, Aaron P.;
- Properzi, Michael J;
- Buckley, Rachel F.;
- Jacobs, Heidi I.L.;
- Hanseeuw, Bernard;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Defining the ATN framework using longitudinal biomarker trajectories reveals an emerging amyloid accumulation group.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.068001
By:
- Boyle, Rory Thomas;
- Coughlan, Gillian T;
- Properzi, Michael J;
- Archdeacon, Claire;
- Chou, Hsiang‐Chin Lori;
- Klinger, Hannah;
- Jacobs, Heidi I.L.;
- Papp, Kathryn V.;
- Amariglio, Rebecca E.;
- Farrell, Michelle E.;
- Donohue, Michael C.;
- Hohman, Timothy J.;
- Mormino, Elizabeth C.;
- Hanseeuw, Bernard J;
- Chhatwal, Jasmeer P.;
- Rentz, Dorene M.;
- Price, Julie C;
- Johnson, Keith A.;
- Schultz, Aaron P.;
- Sperling, Reisa A.
Publication type:
Article
Cerebrovascular injury markers explain the effect of systemic vascular risk on cognitive decline in older adults with lower amyloid burden.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.066686
By:
- Shirzadi, Zahra;
- Yau, Wai‐Ying Wendy;
- Rabin, Jennifer S.;
- Buckley, Rachel F.;
- Properzi, Michael J;
- Fu, Jessie Fanglu;
- Hsieh, Stephanie;
- Thibault, Emma G.;
- Mojiri‐Forooshani, Parisa;
- Goubran, Maged;
- MacIntosh, Bradley J.;
- Black, Sandra E.;
- Price, Julie C;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Chhatwal, Jasmeer P.;
- Schultz, Aaron P.
Publication type:
Article
Menopause age and hormone therapy use moderate PET tau and amyloid association: findings from the Wisconsin Registry for Alzheimer Prevention.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.062007
By:
- Coughlan, Gillian T;
- Koscik, Rebecca Langhough;
- Betthauser, Tobey J;
- Boyle, Rory Thomas;
- Jonaitis, Erin M.;
- Wenzel, Allen;
- Christian, Bradley T;
- Gleason, Carey E.;
- Klinger, Hannah;
- Properzi, Michael J;
- Schultz, Aaron P.;
- Hanseeuw, Bernard J;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Johnson, Sterling C.;
- Buckley, Rachel F.
Publication type:
Article
Lower in‐vivo locus coeruleus integrity is associated with lower cortical thickness in older individuals with elevated Alzheimer's pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.067421
By:
- Engels, Nina;
- Hsieh, Stephanie;
- Schneider, Christoph;
- Prokopiou, Prokopis C.;
- Schultz, Aaron P.;
- Riphagen, Joost M.;
- Koops, Elouise A.;
- Hanseeuw, Bernard;
- Rentz, Dorene M.;
- Sperling, Reisa A.;
- Johnson, Keith A.;
- Jacobs, Heidi I.L.
Publication type:
Article
The role of cortical microstructural changes on longitudinal accumulation of tau and cognitive decline in at risk older adults.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.065744
By:
- Gagliardi, Geoffroy Pierre;
- Rodriguez‐Vieitez, Elena;
- Montal, Victor;
- Sepulcre, Jorge;
- Diez, Ibai Palacio;
- Lois, Cristina;
- Hanseeuw, Bernard;
- Schultz, Aaron P.;
- Properzi, Michael J;
- Papp, Kathryn V.;
- Marshall, Gad A;
- Fortea, Juan;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Vannini, Patrizia
Publication type:
Article
Longitudinal tau burden partially mediates synergistic influence of vascular risk and amyloid‐beta on cognitive decline in clinically normal older adults.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.067488
By:
- Yau, Wai‐Ying Wendy;
- Shirzadi, Zahra;
- Rabin, Jennifer S.;
- Properzi, Michael J;
- Schultz, Aaron P.;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Chhatwal, Jasmeer P.
Publication type:
Article
AD‐causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.067186
By:
- Schultz, Stephanie A.;
- Allegri, Ricardo Francisco;
- Schultz, Aaron P;
- Goate, Alison;
- Levey, Allan I.;
- Fagan, Anne M.;
- Hanseeuw, Bernard J;
- Koeppe, Robert A.;
- Gordon, Brian A.;
- Cruchaga, Carlos;
- Karch, Celeste M.;
- Chen, Charles D.;
- Xiong, Chengjie;
- Jack, Clifford R.;
- Fitzpatrick, Colleen D;
- McDade, Eric;
- Chui, Helena C;
- Mori, Hiroshi;
- Lee, Jae‐Hong;
- Noble, James M
Publication type:
Article
Microglia‐specific Alzheimer's disease polygenic risk score is associated with amyloid‐β, tau, and microglial activation.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.061819
By:
- Yang, Hyun‐Sik;
- Teng, Ling;
- Kang, Daniel;
- Menon, Vilas;
- Ge, Tian;
- Finucane, Hilary;
- Schultz, Aaron P.;
- Properzi, Michael J;
- Klein, Hans‐Ulrich;
- Chibnik, Lori B.;
- Schneider, Julie A;
- Bennett, David A;
- Hohman, Timothy J.;
- Mayeux, Richard;
- Johnson, Keith A.;
- De Jager, Philip L;
- Sperling, Reisa A.
Publication type:
Article
Longitudinal tau burden partially mediates synergistic influence of vascular risk and amyloid‐beta on cognitive decline in clinically normal older adults.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.068274
By:
- Yau, Wai‐Ying Wendy;
- Shirzadi, Zahra;
- Rabin, Jennifer S.;
- Properzi, Michael J;
- Schultz, Aaron P.;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Chhatwal, Jasmeer P.
Publication type:
Article
AD‐causing variants that affect PSEN1 transmembrane domains are associated with faster neurodegeneration and cognitive decline compared to those affecting cytoplasmic domains.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, p. 1, doi. 10.1002/alz.068221
By:
- Schultz, Stephanie A.;
- Allegri, Ricardo Francisco;
- Schultz, Aaron P.;
- Goate, Alison;
- Levey, Allan I.;
- Fagan, Anne M.;
- Hanseeuw, Bernard J;
- Koeppe, Robert A.;
- Gordon, Brian A.;
- Cruchaga, Carlos;
- Karch, Celeste M.;
- Chen, Charles D.;
- Xiong, Chengjie;
- Jack, Clifford R.;
- Fitzpatrick, Colleen D;
- McDade, Eric;
- Chui, Helena C;
- Mori, Hiroshi;
- Lee, Jae‐Hong;
- Noble, James M
Publication type:
Article
Plasma IL‐12/IFN‐γ axis predicts cognitive trajectories in cognitively unimpaired older adults.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 645, doi. 10.1002/alz.12399
By:
- Yang, Hyun‐Sik;
- Zhang, Can;
- Carlyle, Becky C.;
- Zhen, Sherri Y.;
- Trombetta, Bianca A.;
- Schultz, Aaron P.;
- Pruzin, Jeremy J.;
- Fitzpatrick, Colleen D.;
- Yau, Wai‐Ying W.;
- Kirn, Dylan R.;
- Rentz, Dorene M.;
- Arnold, Steven E.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Chhatwal, Jasmeer P.;
- Tanzi, Rudolph E.
Publication type:
Article
The combined influence of beta‐amyloid and vascular risk on prospective brain atrophy in clinically normal individuals.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.049730
By:
- Rabin, Jennifer S;
- Pruzin, Jeremy J;
- Schultz, Aaron P;
- Scott, Matthew R;
- Hampton, Olivia L;
- Hsieh, Stephanie;
- Yang, Hyun‐Sik;
- Yau, Wai‐Ying;
- Hedden, Trey;
- Rentz, Dorene M;
- Johnson, Keith A;
- Sperling, Reisa A;
- Chhatwal, Jasmeer P
Publication type:
Article
Associations between remote cognitive testing on an individual's own digital device and amyloid burden on neuroimaging in clinically normal older adults: Results from Boston Remote Assessment for Neurocognitive Health (BRANCH).
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056209
By:
- Papp, Kate V.;
- Rentz, Dorene M.;
- Buckley, Rachel F.;
- Schneider, Olivia R;
- Hsieh, Stephanie;
- Soberanes, Daniel;
- Properzi, Michael J;
- Schultz, Aaron P.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Amariglio, Rebecca E.
Publication type:
Article
Sequential early cognitive changes sensitive to rising beta‐amyloid and tau pathology in preclinical AD.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056315
By:
- Farrell, Michelle E.;
- Papp, Kate V.;
- Buckley, Rachel F.;
- Jacobs, Heidi I.L.;
- Schultz, Aaron P;
- Properzi, Michael J;
- Vannini, Patrizia;
- Hanseeuw, Bernard;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Sperling, Reisa A.
Publication type:
Article
Longitudinal associations between amyloid and tau‐PET: Impact for prevention trials.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056208
By:
- Hanseeuw, Bernard;
- Jacobs, Heidi I.L.;
- Becker, Alex;
- Buckley, Rachel F.;
- Properzi, Michael J.;
- Farrell, Michelle E.;
- Schultz, Aaron P.;
- Sanchez, Justin S.;
- Chhatwal, Jasmeer P.;
- Price, Julie C.;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Associations between biomarker status (amyloid, tau) and risk for progression to MCI/Dementia in the Harvard Aging Brain Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056231
By:
- Papp, Kate V.;
- Rentz, Dorene M.;
- Winskill, Carolyn;
- Betensky, Rebecca A.;
- Amariglio, Rebecca E.;
- Schultz, Aaron P.;
- Johnson, Keith A.;
- Sperling, Reisa A.
Publication type:
Article
Self‐reported history of estrogen hormone therapy differentiates rates of amyloid accumulation (PiB‐PET) relative to males: Findings from the Harvard Aging Brain Study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056069
By:
- Rubinstein, Zoe B.;
- Buckley, Rachel F.;
- Scott, Matthew R.;
- Manning, Lyssa K.;
- Mayblyum, Danielle V.;
- Thibault, Emma G.;
- Jacobs, Heidi I.L.;
- Farrell, Michelle E.;
- Properzi, Michael J.;
- Rabin, Jennifer S.;
- Chhatwal, Jasmeer P.;
- Lois, Cristina;
- Rentz, Dorene;
- Price, Julie C.;
- Schultz, Aaron P.;
- Sperling, Reisa A.;
- Johnson, Keith A.
Publication type:
Article
Cortical microstructure is associated with tau burden and predicts cognitive decline and clinical progression in healthy older adults.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.053011
By:
- Rodriguez‐Vieitez, Elena;
- Montal, Victor;
- Sepulcre, Jorge;
- Lois, Cristina;
- Hanseeuw, Bernard;
- Vilaplana, Eduard;
- Schultz, Aaron P.;
- Properzi, Michael J;
- Scott, Matthew R.;
- Amariglio, Rebecca E.;
- Papp, Kate V.;
- Marshall, Gad A;
- Fortea, Juan;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Vannini, Patrizia
Publication type:
Article
The location of PSEN1 pathogenic variants in transmembrane vs. cytoplasmic domains may alter neurodegenerative and cognitive trajectories: Findings from the DIAN study.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.050864
By:
- Schultz, Stephanie A.;
- Schultz, Aaron P.;
- Joseph‐Mathurin, Nelly;
- McDade, Eric;
- Klunk, William E.;
- Fox, Nick C.;
- Levin, Johannes;
- Hassenstab, Jason;
- Goate, Alison M.;
- Hanseeuw, Bernard J;
- Lee, Jae‐Hong;
- Fitzpatrick, Colleen D.;
- Jucker, Mathias;
- Allegri, Ricardo Francisco;
- Benzinger, Tammie L.S.;
- Berman, Sarah;
- Chui, Helena C.;
- Cruchaga, Carlos;
- Fagan, Anne M.;
- Gordon, Brian A.
Publication type:
Article
Extraneous neuroimaging factors do not contribute to sex differences in flortaucipir signal: Analysis of skull binding and partial volume effects.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.056051
By:
- Scott, Matthew R.;
- Edwards, Natalie C;
- Properzi, Michael J;
- Jacobs, Heidi I.L.;
- Price, Julie C;
- Manning, Lyssa K;
- Mayblyum, Danielle V.;
- Rubinstein, Zoe B.;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Sperling, Reisa A.;
- Schultz, Aaron P.;
- Buckley, Rachel F.
Publication type:
Article
Distinct contributions of longitudinal tau and amyloid to decline in various cognitive domains in preclinical AD: Neuropsychology/early detection of cognitive decline with neuropsychological tests.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 6, p. 1, doi. 10.1002/alz.046075
By:
- Farrell, Michelle E.;
- Papp, Kathryn V.;
- Jacobs, Heidi I.L.;
- Buckley, Rachel F.;
- Properzi, Michael J.;
- Schultz, Aaron P.;
- Hanseeuw, Bernard;
- Rentz, Dorene M.;
- Johnson, Keith A.;
- Sperling, Reisa A.
Publication type:
Article

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