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- Title
Multidimensional alcohol craving scale and [123I] Iodobenzamide SPECT as predictors of early relapse in alcohol-dependent patients.
- Authors
Guardia-Serecigni, Josep; Estorch, Montserrat; Surkov, Sergey; del Valle Camacho, M<sup>ª</sup>; García-Ribas, Guillermo
- Abstract
Background: The Multidimensional Alcohol Craving Scale (MACS) and Single Photon Emission Computerized Tomography (SPECT) with 123I-iodobenzamide (123I-IBZM) can be useful tools for assessing relapse risk in early recovery from alcohol-dependency. The aim of this study was to assess possible relationships between MACS score, 123I-IBZM binding and time to first heavy drinking day (TFHD) after detoxification treatment. Methods: Nineteen alcohol-dependent in-patients were evaluated by MACS scale and an 123I-IBZM-SPECT, performed following alcohol detoxification treatment. At discharge, participants were advised to take naltrexone 50 mg/day for relapse prevention. TFHD was assessed over a 12-week follow up. Results: The MACS score at the beginning of the detoxification process and naltrexone treatment after detoxification were independent predictive factors for TFHD. Conclusions: The MACS scale is a better predictor of TFHD than IBZM binding. It is simple, non-invasive and inexpensive and appears to be a useful instrument both for clinical practice and for research.
- Subjects
ALCOHOL drinking; ALCOHOL Dependence Scale; DETOXIFICATION (Substance abuse treatment); PHOTON emission; TOMOGRAPHY; NALTREXONE
- Publication
Adicciones, 2011, Vol 23, Issue 2, p157
- ISSN
0214-4840
- Publication type
Article
- DOI
10.20882/adicciones.159