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- Title
Two New Meroterpenes from the Mangrove Endophytic Fungus Aspergillus sp. 085241B.
- Authors
Song, Yong-Xiang; Qiao, Li-Tao; Wang, Jia-Jian; Zeng, Hua-Ming; She, Zhi-Gang; Miao, Cheng-Du; Hong, Kui; Gu, Yu-Cheng; Liu, Lan; Lin, Yong-Cheng
- Abstract
Two new meroterpenes, 'acetoxydehydroaustin B' ( 1) and '1,2-dihydro-acetoxydehydroaustin B' ( 2) were isolated in the form of a mixed crystal from the mangrove endophytic fungus Aspergillus sp. 085241B. Their structures and absolute configurations were determined by extensive analysis of their spectra and X-ray diffraction data. In a preliminary bioassay, the mixed crystal did not exhibit activities against cancer cell lines of MDA-MB-435, SKBR3, HepG2, HEP3B, PC-3, and A549, as well as against α-glucosidase and tyrosinase.
- Subjects
TERPENES; ASPERGILLUS; ENDOPHYTIC fungi; MANGROVE plants; SPECTRUM analysis; X-ray diffraction
- Publication
Helvetica Chimica Acta, 2011, Vol 94, Issue 10, p1875
- ISSN
0018-019X
- Publication type
Article
- DOI
10.1002/hlca.201100111