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- Title
Association Between a Germline OCA2 Polymorphism at Chromosome 15q13.1 and Estrogen Receptor–Negative Breast Cancer Survival.
- Authors
Azzato, Elizabeth M.; Tyrer, Jonathan; Fasching, Peter A.; Beckmann, Matthias W.; Ekici, Arif B.; Schulz-Wendtland, Rüdiger; Bojesen, Stig E.; Nordestgaard, Børge G.; Flyger, Henrik; Milne, Roger L.; Arias, José Ignacio; Menéndez, Primitiva; Benítez, Javier; Chang-Claude, Jenny; Hein, Rebecca; Wang-Gohrke, Shan; Nevanlinna, Heli; Heikkinen, Tuomas; Aittomäki, Kristiina; Blomqvist, Carl
- Abstract
Background: Traditional prognostic factors for survival and treatment response of patients with breast cancer do not fully account for observed survival variation. We used available genotype data from a previously conducted two-stage, breast cancer susceptibility genome-wide association study (ie, Studies of Epidemiology and Risk factors in Cancer Heredity [SEARCH]) to investigate associations between variation in germline DNA and overall survival.
- Subjects
BREAST cancer; CANCER patients; CANCER treatment; DNA; ESTROGEN
- Publication
JNCI: Journal of the National Cancer Institute, 2010, Vol 102, Issue 9, p650
- ISSN
0027-8874
- Publication type
Article
- DOI
10.1093/jnci/djq057